Drug Discovery World

JULY 5, 2023

Global Cancer Segment Market Manager at Agilent Technologies, recently sat down with DDW Editor Reece Armstrong to tell us about the developments in the ‘golden age’ of cancer research. RA: What is the current state of the cancer research industry? RA: How is Agilent supporting cancer research? Mark Garner, PhD.,

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Drug Discovery World

OCTOBER 4, 2022

We found out that Omicron infection protects against flu, studies in potential treatments for severe Covid have shown promise, and new genetic insights into ME and CSF were revealed that could have implications in long Covid. . Study reveals first genetic links in ME and Chronic Fatigue Syndrome .

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Scienmag

APRIL 27, 2021

First-of-its-kind advance holds promise for making new strides in research, treatments Irvine, Calif., April 27, 2021 — University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer’s disease.

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Roots Analysis

FEBRUARY 26, 2024

Whether it was a common cold or a genetic disease, prayers and sacrifices to the gods were the only hope of a remedy at such times. It is possible that the legend of Big Foot may be based on an unfortunate person suffering from elephantiasis or gigantism or some other genetic predisposition that would have rendered him abnormal.

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Drug Discovery World

OCTOBER 26, 2022

An international team of scientists have engineered protein banana lectin, or BanLec, to create a new version that can fight off a range of viruses without unwanted side effects. . The researchers also showed that H84T BanLec protected mice from getting infected by the flu virus. .

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Advarra

JANUARY 11, 2024

The applications of mRNA-based therapies in cancer research represent one of the next groundbreaking steps toward improved cancer treatments. While mRNA usage has played several roles in clinical research , oncology researchers in particular are eager to explore the possibilities of mRNA-based cancer vaccines.

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Pharmaceutical Technology

MAY 8, 2023

Innovation S-curve for the pharmaceutical industry Zinc-finger nucleases is a key innovation area in pharmaceutical Zinc finger nucleases (ZFNs) are tools used in genetic engineering to cleave a chosen genomic sequence. ZFNs are also used to create a new generation of genetic disease models called isogenic human disease models.

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pharmaphorum

DECEMBER 24, 2020

The US National Institutes of Health said that the research it had co-funded used AI to transform a bacterial protein into a new research tool. It was led by researchers in the lab of Dr Lin Tian, principal investigator at the University of California Davis School of Medicine.

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XTalks

MARCH 28, 2024

In recent years, the initiative has garnered considerable attention and helped increase education and research funding and provide better treatment options to fight this disease. For CRC, treatment options that are targeting genetic mutations such as BRAF , KRAS and HER2 have been developed.

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Drug Discovery World

NOVEMBER 16, 2022

TAC01-HER2 is a novel cell therapy that consists of genetically engineered autologous T cells expressing T-cell Antigen Coupler (TAC) that recognises HER2. . “The interim safety and efficacy data show that TAC01-HER2 could potentially improve the lives of cancer patients with significant unmet medical need.” .

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Genetic Engineering Engineer Genetics Trials 52

pharmaphorum

FEBRUARY 18, 2021

Researchers from the University of Texas Medical Branch based their findings on lab tests using SARS-CoV-2 coronaviruses that were genetically engineered to have the same mutations as those in the strain that is causing scientists so much concern.

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Bioengineer

JULY 21, 2021

Researchers have proposed a new scoring system for wound healing in mice based on parameters in each phase of healing, as described in an article in the peer-reviewed journal Stem Cells and Development. . publishers is known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research.

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Genetic Engineering Development Engineer Genetics 52

Cloudbyz

MARCH 5, 2024

In the intricate dance of drug discovery and development, two protagonists emerge as the cornerstones of modern medicine: biologics and small molecules. In both cases, clinical research must be meticulously designed to address these complexities. Identifying and minimizing these effects is a critical part of the development process.

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Drug Discovery World

JANUARY 18, 2024

New research has brought stem cell transplantation without immune suppression closer to reality. Researchers at the University of Arizona Health Sciences say they are one step closer to understanding immunological rejection, a barrier to regenerative medicine, after genetically modifying pluripotent stem cells to evade immune recognition.

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pharmaphorum

MARCH 10, 2021

The study suggests that serum taken from patients injected with the mRNA shot, also known as BNT162b2, was able to neutralise a genetically engineered version of SARS-CoV-2 with the P.1 The latest research is published in the New England Journal of Medicine. 1 – that is worrying health officials around the world. .

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The Pharma Data

SEPTEMBER 1, 2021

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. million adults in the United States.

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Bioengineer

JULY 15, 2021

publishers is known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry’s most widely read publication worldwide.

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Nurses Genetic Engineering Engineer Genetics 52

The Pharma Data

JUNE 1, 2022

Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests. The research was published online recently in Proceedings of the National Academy of Sciences.

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Immune Response Genetic Engineering Engineer Research 52

Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. The researchers duly fed its relevant sequences into an algorithm, which proposed a handful of compounds that cil likely produces.

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Bacteria Engineer Gene Genetics 52

The Pharma Data

OCTOBER 27, 2020

The SAB consists of a group of world-renowned experts in immuno-oncology research and drug development carefully selected to act as advisors to guide the Targovax R&D strategy. He is an internationally recognized key opinion leader, clinical investigator and translational research in mesothelioma. OSLO, Norway , Oct.

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Drug Discovery World

JULY 22, 2022

As a result, researchers are striving to continually improve immuno-oncology approaches using the patient’s own immune cells to combat tumours. Researchers discovered that the IL2 expressed in these mice allowed these TILs to eradicate the tumours and metastases present, similar to ACT therapy inpatients 5.

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The Pharma Data

JULY 27, 2021

Acquisition Complements Amgen’s Antibody Research Capabilities Across Therapeutic Areas Acquisition Includes a Portfolio of Early-Stage Oncology Assets, Including a Phase 1 Bispecific Antibody for Patients With Advanced Prostate Cancer. executive vice president of Research and Development at Amgen. Reese, M.D.,

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The Pharma Data

JANUARY 19, 2021

In the paper, researchers from Johns Hopkins University and elsewhere found a natural long-form transactivating CRISPR RNA (tracr-L) in Streptococcus pyogenes that functions to downregulate its endogenous CRISPR-Cas9 system. But altering the tracr-L with genetic engineering to make it function more like a guide RNA increased CRISPR-Cas9 cuts.

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Bacteria Gene Editing Research RNA 52

Pharmaceutical Technology

FEBRUARY 15, 2023

Innovation S-curve for the pharmaceutical industry Gene splicing using nucleases is a key innovation area in the pharmaceutical industry Nucleases play a fundamental role in the field of recombinant DNA technology, or genetic engineering. Gene splicing using nucleases is used to design gene therapeutics for various genetic disorders.

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Drug Discovery World

FEBRUARY 15, 2023

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Genetically modified T cells stimulated with IL2 are now administered as cell therapy for multiple cancer cell types with beneficial results 3,4.

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Drug Discovery World

SEPTEMBER 28, 2022

The encouraging study was led by Prof Ronit Satchi-Fainaro and PhD student Sabina Pozzi of the Sackler Faculty of Medicine at Tel Aviv University. Satchi-Fainaro and her team tried to inhibit the expression of the protein and its receptors in genetically engineered lab models and in 3D models of primary melanoma and brain metastases.

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XTalks

SEPTEMBER 15, 2022

The order prioritizes research and innovation in a variety of fields, including food, and states that federal investments will be made into the space. While biotech in general is often associated with energy, medicine and pharmaceuticals, it plays a significant role in the food and beverage industry.

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The Pharma Data

SEPTEMBER 8, 2020

About AstraZeneca AstraZeneca (LSE/STO/NYSE: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas – Oncology, Cardiovascular, Renal & Metabolism, and Respiratory & Immunology.

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Scienmag

MARCH 19, 2021

Treatment involving a single injection has long-lasting effects BOSTON – Researchers have used a genetic engineering strategy to dramatically reduce levels of tau–a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer’s disease–in an animal model of the condition.

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The Pharma Data

SEPTEMBER 8, 2020

(LSE/STO/NYSE: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas – Oncology, Cardiovascular, Renal & Metabolism, and Respiratory & Immunology. Cambridge, UK.

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Vaccination Vaccine Containment Clinical Trials 52

Drug Discovery World

FEBRUARY 3, 2023

A research group from the National Institutes of Health has successfully developed a vaccine against Sudan virus (SUDV) based on the licensed Ebola virus (EBOV) vaccine. SUDV, identified in 1976, is one of the four viruses known to cause human Ebolavirus disease. Next, the researchers tested the safety and efficacy of VSV-SUDV in macaques.

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pharmaphorum

SEPTEMBER 13, 2022

In fact, according to Blood Cancer UK research, more than half of UK adults cannot name a single symptom of blood cancer. . Over the past two centuries, researchers have identified more than 100 different types of blood cancer, while most patients may be familiar with the big three (leukaemia, lymphoma, and melanoma).

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Drug Discovery World

MARCH 13, 2023

Between the 24 therapies already approved by the FDA 1 and a marked increase in clinical trials, widespread accessibility to precision medicine feels within reach. Drug discovery researchers usually partner with a CDMO to provide support through the development, manufacturing, and clinical supply required to bring a drug to market.

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Roots Analysis

OCTOBER 22, 2023

RNA therapeutics are a novel class of biopharmaceuticals that harness the power of RNA molecules for the treatment and prevention of a wide range of disorders, including oncological, and genetic disorders as well as infectious diseases. These therapeutics are broadly classified into two categories, namely coding RNAs and non-coding RNAs.

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Drug Discovery World

NOVEMBER 8, 2023

The presentations include: Terence Rabbitts, FRS, FMedSci, Professor, Molecular Immunology, Center for Cancer Drug Discovery, Institute of Cancer Research, on: ‘Intracellular antibodies for drug discovery against hard-to-drug targets’. Chairperson Mark Chiu, on: ‘Strategies to enhance efficacy of a tetraspecific antibody to TNBC and PDAC’.

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Drug Discovery World

NOVEMBER 9, 2023

Novel platforms This session will begin with chariperson’s remarks from Lars Linden, PhD, Vice President, Head, Biologics Research, Bayer HealthCare, which will be followed by a keynote presentation by Agnieszka Kielczewska, PhD, Director, Research, Antibody Discovery and Screening, Biologics Discovery, Amgen.

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Roots Analysis

FEBRUARY 15, 2022

Presently, there are several companies and universities, which are exploring the potential of different gene editing technologies beyond CRISPR for basic research, and the development of gene editing solutions. They also allow genetic material to be added, removed, or altered at particular locations in the genome. Web: [link].

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