pharmaphorum

JULY 7, 2022

As this issue’s contributors discuss, by working together pharma companies and healthcare providers can significantly enhance oncology treatment for patients. Therapeutic cancer vaccine trials have an opportunity to leverage recent interest in vaccine technology to make headway in oncology, says Advanced Clinical’s Christopher Oelkrug.

Vaccination 52

Vaccination Vaccine Life Science Trials 52

XTalks

DECEMBER 20, 2023

Check out this article to learn about the biotech companies that went public this year. The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

pharmaphorum

FEBRUARY 17, 2021

One group excelling in this space is the Genetic Alliance. Their work ranges from developing new services in partnership with the National Health Service (NHS) to working with the All Party Parliamentary Group on Rare, Genetic and Undiagnosed Conditions, and the Department of Health on the UK Strategy for Rare Diseases.

Life Science 97

Life Science Branding Genetics Trials 97

pharmaphorum

NOVEMBER 30, 2020

“Our belief is that patients should understand the challenges associated with drug development and how those challenges impact them personally… It is emotionally challenging for patients who must put their faith in the hands of pharma companies”.

Gene Therapy 105

Gene Therapy Gene Antibody Clinical Trials 105

The Pharma Data

DECEMBER 23, 2020

Eligible patients enrolled in the trial receive treatment with AIM’s flagship pipeline drug Ampligen. The Ampligen EAP protocol is authorized to enroll up to 100 active trial participants, 20 of whom may be Long Haulers. development pipeline for ME/CFS. All study subjects will receive the same Ampligen treatments. AIM ImmunoTech Inc.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Drugs 52

pharmaphorum

FEBRUARY 16, 2021

UK biotech Exscientia has signed a string of partnerships with pharma companies and other research-based organisations to apply its AI-based drug discovery platform. It is vital that we develop treatments that target neuroinflammatory mechanisms underlying dementia.”.

Research 119

Research Drugs Protein Development 119

Drug Discovery World

JANUARY 24, 2023

Virtual clinical trials ‘Virtual’ and ‘technology’ are concepts which are readily exchanged in this industry, but these are more than just buzzwords. The overall virtual clinical trials market is currently valued at $7.8 In early November 2022, two Alzheimer’s drugs were tested head-to-head in a first-ever virtual clinical trial 3.

Clinical Trials 97

Clinical Trials Clinical Trials Drugs Trials 97

pharmaphorum

MAY 4, 2022

Moreover, there is the question of the ethics of using animals, numbering in the millions each year, in clinical trials, which sees most euthanized at the end of the process. The challenge that the pharma industry faces is the lack of better alternatives to animal models.

Drugs 143

Drugs Licensing Licensing Pharma Companies 143

pharmaphorum

FEBRUARY 18, 2021

Researchers from the University of Texas Medical Branch based their findings on lab tests using SARS-CoV-2 coronaviruses that were genetically engineered to have the same mutations as those in the strain that is causing scientists so much concern.

Immune Response 52

Immune Response Genetic Engineering Vaccination Vaccine 52

pharmaphorum

JANUARY 6, 2021

Pharma companies are always talking about moving ‘beyond the pill’, and Pfizer’s new brand identity embodies that – it’s decades old pill-like logo has been replaced with a DNA double helix that it says reflects its commitment to breakthrough science. — Tinglong Dai (@TinglongDai) January 5, 2021.

DNA 116

DNA Branding Vaccination Vaccine 116

pharmaphorum

NOVEMBER 23, 2021

GSK’s head of research, John Lepore, said there is “compelling genetic evidence” showing that reduced HSD17B13 function confers protection to the liver from inflammatory injury that is a characteristic of NASH. Arrowhead said the partnering process for ARO-HSD was competitive and GSK was one of several suitors for the drug.

Sales 52

Sales Drugs Trials RNA 52

pharmaphorum

JUNE 16, 2021

The Scripps Research spinout could be just 18 months away from licensee NovoCodex reporting results of a Chinese phase 2/3 trial of ARX788 as a later-line therapy for HER2-positive breast cancer patients which – if positive – could set the drug on course for regulatory approval in China. It raised $200 million in financing last November.

Sales 53

Sales Antibody Drugs Pharma Companies 53

Drug Discovery World

SEPTEMBER 28, 2022

Its application in pharma, most commonly in drug discovery, has been steadily growing with global partnerships between tech vendors and pharma companies becoming more commonplace. According to Hampleton Patners’ latest Healthtech M&A market report2, digital health companies raised a total of $57.2

Pharma Companies 52

Pharma Companies Drugs In-Vivo Genetics 52

XTalks

JANUARY 15, 2024

From the continuing trend of the rapid adoption of AI tools to the growing use of real-world evidence (RWE) in regulatory decision-making and a focus on enhancing data integrity, find out how clinical trials will evolve in 2024 to shape the future of medical research. percent from 2023 to 2033.

Clinical Trials 105

Clinical Trials Clinical Trials Trials Clinical Research 105

pharmaphorum

SEPTEMBER 18, 2020

But although it was dubbed a “dangerous game”, some companies came out on top… On 6th April 1999, two companies with similar science-based cultures and a shared vision of the pharmaceutical industry came together to form what’s now considered as one of the top ten pharma companies in the world: AstraZeneca.

Pharma Companies 116

Pharma Companies Sales Vaccination Vaccine 116

The Pharma Data

OCTOBER 20, 2020

In hopes to advance the best and brightest, MD Anderson, in partnership with The Focus Fund GP, has launched the Cancer Focus Fund to propel compelling investigational cancer therapies from preclinical development through Phase II clinical trials. Targeted therapies, genetic sequencing, gene editing, immunotherapies.

Clinical Trials 52

Clinical Trials Clinical Trials Gene Editing Trials 52

pharmaphorum

JUNE 2, 2021

In February, the Japanese company reported the results of a 274-patient phase 2 trial which showed that KHK4083 was significantly more effective than placebo at clearing skin lesions at 16 weeks in patients with moderate to severe atopic dermatitis – a condition with more than 60 million sufferers worldwide.

Drugs 52

Drugs Licensing Licensing Sales 52

Pharmaceutical Technology

MAY 24, 2023

By Luisa Sterkel & Joana Loureiro , Tenthpin Consultants The promise and potential of cell and gene therapies (CGT) has emerged in the recent past and currently over 1.500 CGT are registered for clinical trials holding great hope for the treatment of challenging and uncurable diseases.

Clinical Trials 246

Clinical Trials Clinical Trials Gene Therapy Clinical Supply Chain 246

pharmaphorum

OCTOBER 27, 2021

In the same statement, the agency admitted that “there remains some uncertainty about the drug’s clinical benefit”, with a label update occurring shortly after approval that limited Aduhelm’s use to patients with early stages of the disease – the same group as tested in clinical trials for the drug. The challenge of treating Alzheimer’s.

Clinical Trials 75

Clinical Trials Clinical Trials Trials Research 75

Cloudbyz

MAY 19, 2021

The industry marked abundant gene-therapy-related activities, testing, and trials all well funded and financially supported by an influx of angel investors and venture capitalists. The primary drivers for growth include increasing cancer and genetic cases and predicated applicability of CGT as a treatment.

Gene Therapy 52

Gene Therapy Gene Manufacturing Production 52

Delveinsight

SEPTEMBER 27, 2021

Furthermore, the condition carries the risk of differential diagnosis as more than 50 genetic/metabolic diseases are associated with infantile spasms, and many patients have other disorders that cause developmental delays (e.g., Early diagnosis is necessary for better treatment outcomes. cerebral palsy, Down syndrome, tuberous sclerosis, etc.)

Marketing 77

Marketing Hormones Radiology Pharma Companies 77

pharmaphorum

DECEMBER 21, 2020

As it’s just a messenger molecule, it does not affect the body’s own genetic code when it is injected as a vaccine – but what it does do is instruct cells to code for copies of a certain protein. Their technology is based on synthetic messenger RNA – short for ribose nucleic acid – which is a short transcript of a longer DNA code.

Vaccination 90

Vaccination Vaccine Doctors Doctor 90

pharmaphorum

JANUARY 29, 2021

Since Macrae joined the company just four years ago, Sangamo has more than tripled its staff and raised $1.6 It has also built its own manufacturing site and launched partnerships with six big pharma companies. And ultimately we will be able to add genetic influences to diseases that don’t have a genetic cause.

Gene Editing 144

Gene Editing Gene Gene Therapy In-Vivo 144

pharmaphorum

APRIL 26, 2022

Research into the area is being made possible through advancements in technology, such as being able to sequence genes at scale, allowing researchers to gain more detailed genetic data on the microbiome. In the trial, Seres announced that the product candidate had met its primary endpoint, showing a statistically significant 30.2%

Containment 110

Containment Development Production Immune Response 110

Drug Discovery World

FEBRUARY 6, 2024

As AI-designed drugs start to enter large-scale clinical trials, DDW’s Diana Spencer investigates how new digital tools are reinventing and reshaping drug discovery for the future. The company’s platform evaluated more than 11.4

Marketing 69

Marketing Medicine Genome Genomics 69

pharmaphorum

SEPTEMBER 7, 2022

Pharma has a great opportunity ahead of it when it comes to conducting representative clinical trials. The processes used are now seeing huge infrastructure commitments, in order to cement their place in the development of future products and trials. But our drug development processes are not perfect.

Clinical Trials 95

Clinical Trials Clinical Trials Trials Genetics 95

pharmaphorum

MAY 26, 2022

Racial disparities are still commonplace in many clinical trials with white-ethnic groups often overrepresented amongst trial participants. Inadequate clinical trial representations of all populations can therefore leave underrepresented groups vulnerable due to the lack of subgroup-specific data. Unpacking the status quo.

Clinical Trials 138

Clinical Trials Clinical Trials Trials Medicine 138

XTalks

DECEMBER 29, 2022

Given their precise targeting, gene therapies have largely been focused on oncology indications followed by rare genetic diseases. As such, most gene therapies in late-stage clinical trials are in oncology or rare disease indications. By 2030, an estimated 60 cell and gene therapies are expected to receive regulatory approval.

Life Science 52

Life Science Gene Therapy Gene Manufacturing 52

pharmaphorum

APRIL 8, 2021

COVID-19 has been a trial-by-fire showing just how quickly drugs and vaccines can be developed under the right circumstances – but there is much to do to ensure this progress is not lost, said speakers at WIRED Health 2021, including the CEOs of BioNTech and BenevolentAI. . In the UK we have world leading genetic sequencing capabilities.

Development 82

Development Drugs Vaccination Vaccine 82

pharmaphorum

DECEMBER 23, 2020

The American Society of Clinical Oncology (ASCO) annual conference was one of the highlights of the year in cancer research and the fact it was held virtually did not distract from some stunning clinical lung cancer trial results presented by AstraZeneca. In the 500 patient trial, patients treated with Trodelvy lived for a median of 12.1

Marketing 78

Marketing Gene Silencing Gene Drugs 78

Delveinsight

AUGUST 4, 2021

Similarly, genetics, immune response, and environmental factors also influence the occurrence of Neurological Conditions. With the advancement in technology, today diagnostics testing such as neurological examination, brain scans, genetic screening, and other tests are available to examine the occurrence of Neurological Conditions.

Marketing 98

Marketing Genetics Development Clinical Development 98

Drug Discovery World

DECEMBER 14, 2023

As well as the Cancer Research UK Scotland Institute, Cancer Research UK awards grants to research groups at universities and funds Experimental Cancer Medicine Centres (ECMCs) in Glasgow and Edinburgh, which deliver clinical trials of new experimental treatments.

Drugs 75

Drugs Life Science Research Scientist 75

pharmaphorum

MARCH 28, 2022

Built under a government tender, AION Labs comprises four large international pharma companies – AstraZeneca , Merck, Pfizer , and Teva – and another core partner, the Israel Biotech Fund. Yerushalmi states there are numerous ways AI can support the pharma process – from clinical trials to patient stratification.

Pharma Companies 98

Pharma Companies Antibody Protein Development 98

The Pharma Data

NOVEMBER 27, 2020

This week, another pharma company revealed a new technology device that can detect if a patient is infectious or not, while the Russian government published results of its Sputnik V vaccine, claiming it is more than 95 per cent efficient 42 days after the first dose.

Vaccination 52

Vaccination Vaccine Immune Response Marketing 52

pharmaphorum

OCTOBER 26, 2022

For example, at the SSIEM Annual Symposium earlier this month, the company shared data on a new candidate for the treatment of Fabry disease, a rare genetic blood disorder. Chiesi’s approach to these trials presents a clear demonstration of Chiesi’s patient-centricity approach in action. Caring for a global community.

Development 86

Development Trials Marketing Life Science 86

Drug Discovery World

OCTOBER 4, 2022

The pandemic might have affected the number of clinical trials taking place for cell and gene therapies, with activity decreasing by around 15% compared to 2020, but major therapies such as Novartis’ gene therapy drug for spinal muscular atrophy (SMA) Zolgensma still made it to market. . billion, compared to $19.9

Gene Therapy 52

Gene Therapy Drugs Gene Manufacturing 52

XTalks

DECEMBER 13, 2023

Now, let’s delve into the list of the top ten fastest growing biotech companies in 2023, ranked by their compound annual growth rate (CAGR). These companies were identified through The Americas’ Fastest-Growing Companies 2023 list by the Financial Times.

Genetics 111

Genetics Vaccination Vaccine DNA 111