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Genetic screening before prescribing could benefit millions, study finds

pharmaphorum

Four million UK patients could benefit annually from genetic testing before being prescribed common medicines, according to new research. Researchers from the University of East Anglia (UEA) in collaboration with Boots UK and Leiden University analysed 2019 NHS dispensing data across the UK.

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Insights into Precision Dosing with Dr. Howard McLeod and Dr. Sharmeen Roy – Xtalks Life Science Podcast Ep. 163

XTalks

It leverages various patient-specific factors, including genetics, age, weight, organ function and even lifestyle, to determine the most appropriate dosage for each individual. Her career spans pediatric clinical pharmacy, clinical research and pharmacogenomics with leadership roles at University of Chicago Medical Center and PipelineRx.

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Study: Fiber intake reduces cognitive decline risk in older people with apolipoprotein ?4 allele

Medical Xpress

Fiber intake is associated with a lower risk of developing cognitive decline in those old people with the apolipoprotein E ApoE ε4 genotype, regarded as a genetic risk factor linked to the development of Alzheimer's disease.

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Cell and gene therapies: why advanced medicines call for specialised logistics

Pharmaceutical Technology

Genetic mutations, both germline and acquired, are behind a large proportion of the most debilitating and sometimes life-threatening human diseases. A new frontier in cancer research. But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine.

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Lipid nanoparticles and mRNA used to treat hereditary blindness

Drug Discovery World

Oregon State University College of Pharmacy scientists have shown that lipid nanoparticles and messenger RNA could treat blindness associated with a rare genetic condition. . We used these peptides to act as zip codes to deliver nanoparticles carrying genetic materials to the intended address within the eye.” .

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Natural products with potential efficacy against lethal viruses

Scienmag

Review of the life histories of RNA viruses, their genetics, and the compounds that could disrupt them offers hope for curtailment of future pandemics Credit: Illustration: Jennifer Matthews/Scripps Oceanography Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California (..)

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Leading commercial dose (non-sterile) companies in contract marketing

Pharmaceutical Technology

The production of commercial dose non-sterile products such as tablets, capsules, ointments, creams, and powders is rising due to their growing global demand, attributed to increasing demand for anti-ageing products, hereditary factors, genetic mutations, exposure to harmful radiation, and rising geriatric population.

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