Drug Discovery World

FEBRUARY 12, 2024

The Engineering Biology Mission Award was given by UK Research and Innovation (UKRI). Membrane proteins are crucial molecules on the surface of cells with numerous biological functions, such as sensing hormones or cell communication. for drug discovery research appeared first on Drug Discovery World (DDW).

Research 105

Research Drugs Engineer Protein 105

Trialfacts

APRIL 10, 2024

With so many people having to deal with this illness, it’s no wonder researchers have been working tirelessly to try and improve the lives of those with type 2 diabetes. That’s where researchers from the University of Adelaide come in. Participants may experience improvements in their blood glucose regulation.

Research 52

Research Hormones Regulation Drugs 52

BioTech 365

SEPTEMBER 18, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Yeast and bacteria together biosynthesize plant hormones for weed control.Plants regulate their growth and development using hormones, including a group called strigolactones that prevent excessive budding and … Continue (..)

Hormones 40

Hormones Bacteria Regulation Development 40

ProRelix Research

SEPTEMBER 26, 2023

Endocrine disorders result from the improper functioning of endocrine glands that secrete and regulate hormones responsible for functioning of various organs.

Hormones 52

Hormones Development Regulation Research 52

Pharmaceutical Technology

JUNE 13, 2023

The combination therapy is intended to treat hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer in adult patients, after recurrence or progression on or after an endocrine-based regimen. AstraZeneca stated that its NDA is being reviewed under Project Orbis.

HR 245

HR Hormones Trials Protein 245

Scienmag

JANUARY 26, 2021

Hormone treatment can help reduce cysts in fruit fly renal tubules, according to Cassandra Millet-Boureima and Chiara Gamberi Credit: Concordia University A hormone commonly associated with sleep-wake regulation has been found to reduce cysts in fruit flies, according to Concordia researchers.

Hormones 52

Hormones Research Regulation Medicine 52

XTalks

NOVEMBER 26, 2020

In addition to innovative new antibody drugs and mRNA vaccines, researchers have found that the sleep-regulating hormone melatonin may also offer protection against COVID-19. Melatonin, which regulates the body’s circadian rhythm and sleep-wake cycle, is also available in pill form for use as a sleep aid.

Research 98

Research Hormones Protein Regulation 98

XTalks

JANUARY 9, 2024

The thyroid plays a critical role in the body by producing hormones that regulate metabolism, heart rate and body temperature among others. Types of Thyroid Conditions There are several different thyroid conditions, with each affecting thyroid hormone production or the gland’s structure, leading to a range of health issues.

Hormones 105

Hormones Antibody Trials Production 105

Scienmag

DECEMBER 8, 2020

In an article published in the Journal of Pineal Research, researchers at São Paulo State University and collaborators describe a set of genes potentially regulated by the ‘sleep hormone’ in some types of tumor A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin (..)

Hormones 40

Hormones Regulation Gene Research 40

pharmaphorum

JANUARY 17, 2022

Under the joint research plan, the Danish giant will work with EraCal to identify novel drug targets relevant for food intake regulation and additional metabolic phenotypes. After securing FDA approval for Wegovy last year, Novo Nordisk is strengthening its position in the obesity space through a collaboration with EraCal Therapeutics.

FDA Approval 119

FDA Approval In-Vitro Regulation Hormones 119

Scienmag

MARCH 29, 2021

No FDA regulations in place to alert patients when medication is derived from animals More physicians and pharmacists are advocating for patients to be made aware of animal byproducts contained in common medications, according to new research in the Journal of Osteopathic Medicine.

Containment 50

Containment Hormones Regulation Medicine 50

Pharmaceutical Technology

FEBRUARY 24, 2023

Douglas provides products in various therapeutic areas which include psoriasis, eczema, dermatitis, chicken pox, constipation, laxative, neonatal, hormone regulation, dermatology, cardiovascular and measles, among others. Douglas collaborates with scientific researchers and external medical experts to advance clinical research.

Contract Manufacturing 100

Contract Manufacturing Dermatology Hormones Production 100

Pharmaceutical Technology

FEBRUARY 24, 2023

Douglas provides products in various therapeutic areas which include psoriasis, eczema, dermatitis, chicken pox, constipation, laxative, neonatal, hormone regulation, dermatology, cardiovascular and measles, among others. Douglas collaborates with scientific researchers and external medical experts to advance clinical research.

Contract Manufacturing 100

Contract Manufacturing Dermatology Hormones Production 100

The Pharma Data

OCTOBER 21, 2020

21, 2020 — Low levels of thyroid hormone during pregnancy may contribute to the development of attention deficit hyperactivity disorder in the child, new research suggests. children, according to the researchers. Many of those genes are regulated by thyroid hormones, the team noted. WEDNESDAY, Oct.

Hormones 52

Hormones Gene Research Medicine 52

XTalks

NOVEMBER 15, 2021

Now, new research shows that the brain hormone serotonin may cause gut inflammation that could trigger flare-ups in Crohn’s disease. McMaster University researchers found that high levels of serotonin blocked the cellular process of autophagy in the gut, which cells use to destroy and remove their damaged cellular components.

Hormones 98

Hormones Regulation Research Production 98

Pharmaceutical Technology

OCTOBER 13, 2022

Melatonin has a prescription-only status and is strictly regulated in the UK, making this the first time it has been approved for use in this indication. The hormone is produced endogenously in the body by the pineal gland. The therapeutic is meant for youth with ADHD aged 6-17 years who found sleep hygiene measures inadequate.

Drugs 147

Drugs Hormones Sales Medicine 147

Pharmaceutical Technology

MARCH 10, 2023

Pharmaceutical and biotechnology industries widely use freeze-drying systems to protect vaccines, antibodies, antibiotics such as penicillin, blood plasma, proteins, enzymes, hormones, viruses, and bacteria from heat and minimise their biological activity.

Manufacturing 147

Manufacturing Production Containment Antibody 147

XTalks

AUGUST 15, 2023

Some research has found a possible correlation between Yellow 5 and heightened hyperactivity in children, while rat studies exploring Yellow 6 have uncovered potential links to tumors in the testes and adrenal glands. That’s because American pork contains growth hormones. It’s not just used to wash chicken, either.

Hormones 98

Hormones Containment Production Packaging 98

XTalks

SEPTEMBER 28, 2023

This is because the US has more lenient food ingredient regulations, potentially exposing consumers to carcinogens and harmful chemicals. Most research, however, suggests that the amount of titanium dioxide ingested from food is minimal, posing little to no risk to human health.

Hormones 52

Hormones Containment Production Cosmetics 52

Drug Discovery World

DECEMBER 19, 2023

Despite VMS, or hot flushes, being a common symptom of menopause, until now, hormone replacement therapy (HRT) was the only treatment. Lack of scientific advancement Before menopause, there is a balance between oestrogen, and the protein neurokinin B (NKB), which regulates the brain’s temperature control centre.

Hormones 59

Hormones Clinical Trials Clinical Trials Medicine 59

The Pharma Data

APRIL 11, 2023

Bayer is progressing novel research around its prostate cancer treatment darolutamide. Both small molecule inhibitors in Immuno-Oncology are being jointly developed in a strategic research alliance with the German Cancer Research Center (DKFZ) in Heidelberg, Germany.

Research 40

Research Clinical Trials Clinical Trials Trials 40

XTalks

NOVEMBER 2, 2021

The study , which was published last week in the Journal of Exposure Science & Environmental Epidemiology , showed that hormone-disrupting chemicals, known as phthalates, were prevalent in a wide range of fast-food items. Phthalates are a widely used type of plasticizer, used to make plastic softer and give it more flexibility.

Containment 96

Containment Hormones Contamination Packaging 96

XTalks

MARCH 13, 2024

Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects. Secondly, other funded research is exploring differential gene expression regulated by DNA methylation.

Gene Therapy 111

Gene Therapy Gene Life Science DNA 111

Roots Analysis

OCTOBER 24, 2023

Owing to the advancement in clinical pharmacology and oncology domain, and the rising demand for targeted therapeutics and precision medicines, high potency active pharmaceutical ingredients (HPAPIs) and cytotoxic drugs have become one of the key areas of interest to researchers and drug manufacturers across the globe.

Manufacturing 40

Manufacturing Hormones Contamination Containment 40

pharmaphorum

JUNE 16, 2022

It is tailored to patients being treated with Lilly’s oncology drugs – which include blockbuster CDK 4/ 6 inhibitor Verzenio (abemaciclib) for hormone receptor-positive, HER2-negative breast cancer – and is expected to make its debut in Germany in July.

Hormones 95

Hormones Pharma Companies Regulation Drugs 95

pharmaphorum

AUGUST 16, 2022

Everest has meanwhile also filed for approval of the drug in the same indication with regulators in South Korea, Taiwan and Hong Kong. “Trodelvy is the cornerstone of our solid tumour portfolio,” commented Bill Grossman, Gilead’s head of oncology clinical research.

Licensing 52

Licensing Licensing Hormones Drugs 52

The Pharma Data

NOVEMBER 21, 2021

director of the Division of General Endocrinology in the FDA’s Center for Drug Evaluation and Research. People with achondroplasia have a genetic mutation that causes a certain growth regulation gene called fibroblast growth factor receptor 3 to be overly active, which prevents normal bone growth. Inheritance is autosomal dominant.[1][2]

FDA Approval 52

FDA Approval Drugs Regulation Genetics 52

Delveinsight

AUGUST 31, 2021

FDA’s Green Flag to Ascendis’s Once-Weekly SKYTROFA for Treatment of Pediatric Growth Hormone Deficiency. Growth Hormone Deficiency , commonly known as dwarfism, can constitute short stature and complications with metabolism, which arise due to inadequate production of growth hormones by the pituitary gland inside the body.

Hormones 60

Hormones FDA Approval Development Drugs 60

XTalks

NOVEMBER 6, 2023

This move comes after the FDA National Center for Toxicological Research, the Center for Food Safety and Applied Nutrition and Toxicologic Pathology Associates in the US uncovered new evidence pointing to brominated vegetable oil’s potential harm.

Hormones 59

Hormones Manufacturing Research Production 59

Drug Discovery World

AUGUST 21, 2023

Dr Christian Hendershot, Director of the Clinical and Translational Addiction Research Programme at the University of North Carolina at Chapel Hill, is conducting one of the new trials into addiction. GLP-1 is a hormone that is produced naturally in the brain and the gut in response to food ingestion.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Drugs 52

XTalks

MAY 31, 2023

The research demonstrates that excessive intake of table salt can elevate several indicators for dementia and Alzheimer’s disease. The research team utilized a mouse model, feeding the mice a high sodium solution (two percent sodium chloride) in their drinking water for 12 weeks, and noted their blood pressure throughout the study.

Protein 111

Protein Hormones Containment Branding 111

XTalks

OCTOBER 11, 2023

They mimic the action of GLP-1, a hormone that helps regulate blood sugar levels by enhancing insulin secretion. There was also a high rate of biliary disease in patients taking either liraglutide or semaglutide, but the researchers said the difference was “not found to be statistically significant.”

Drugs 59

Drugs Insulin Hormones FDA Approval 59

XTalks

NOVEMBER 2, 2021

The test measures levels of C-peptide protein in the blood, which is a byproduct of insulin synthesis that is released from the pancreas along with the hormone. Related: Researchers Develop World’s First Glucose Saliva Test for Diabetes. Currently, the only treatment for type 1 diabetes is insulin therapy.

Insulin 98

Insulin Protein Hormones Regulation 98

Pfizer

JANUARY 27, 2023

Pfizer Responds to Research Claims carterda Fri, 01/27/2023 - 19:48 Pfizer Responds to Research Claims Friday, January 27, 2023 - 08:00pm Share New York, N.Y., In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. and around the world.

Research 112

Research Vaccination Vaccine Drugs 112

Olympian Clinical Research

JULY 12, 2022

Serotonin is a neurotransmitter that plays a role in mood regulation. This type of depression may occur after childbirth and is thought to be caused by a sudden hormone change. PMDD is thought to be caused by a combination of hormonal and brain chemistry changes. Olympian Clinical Research frequently hosts studies on depression.

Hormones 94

Hormones Clinical Research Doctors Doctor 94

XTalks

JUNE 27, 2022

The BRAF gene regulates cell growth, proliferation and apoptosis. Both Tafinlar and Mekinist target the RAS/RAF/MEK/ERK pathway , which regulates cell growth and survival; however, each affects different kinases. Tafinlar + Mekinist is also the first of its kind approved for use in pediatric patients.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Regulation 52

XTalks

JULY 2, 2021

Currently, there is no scientific evidence to suggest that the vaccines induce any hormonal changes that would lead to irregular periods. Given the growing accounts of the phenomenon, some researchers have started looking into the issue. This had led some to wonder whether period changes may be a potential side effect of the vaccines.

Vaccination 105

Vaccination Vaccine Protein Immune Response 105