Drug Discovery World

NOVEMBER 7, 2022

The study’s first author Randy Watson, a postdoctoral researcher in the Lander lab, spent more than a year devising a recipe for stabilising cereblon in association with a ubiquitin-system partner protein, in order to image it with low-temperature electron microscopy (cryo-EM). . Switching to a ‘closed’ conformation .

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Drug Discovery World

JANUARY 30, 2024

To achieve this, we need greater collaboration between academia, therapy developers and manufacturing equipment developers.” Stella Vnook , CEO, Likarda , notes that a s more regenerative therapy options come to the market, patients will demand access to the treatments, often using the court system. She

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Gene Therapy Manufacturing Gene Clinical Trials 71

Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

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The Pharma Data

JANUARY 31, 2021

” Clover and GSK also decided to discontinue their partnership to evaluate the S-Trimer COVID-19 vaccine candidate with GSK’s pandemic adjuvant system. Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology.

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Vaccination Vaccine Trials Protein 52

Drug Discovery World

MAY 22, 2023

But are these price tags a barrier to access? From private plans to government programmes, there are workable systems that support CGTs, proven by MediCare’s support of CAR-T and the UK’s National Health Service coverage. CGTs are classified as ‘living drugs’ and are much more complex entities than other biologics.

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Gene Therapy Gene Drugs Contamination 52

XTalks

AUGUST 17, 2020

To learn more about innovations in the field, Xtalks spoke to Anish Suri, PhD, president and chief scientific officer of Cue Biopharma about the company’s initiatives in the development of immune-based biological compounds for the treatment of cancers and autoimmune diseases. Cell-Based Immunotherapy vs. Immune Biologics.

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Intouch Solutions

APRIL 11, 2024

However, in keeping with the nature of this short article, I will highlight a couple of the most relevant activities: Data Aggregation Strategy and Analysis AI-powered systems gather data from diverse sources. Pre-Clinical : Deeper comprehension of the impacts and outcomes associated with a particular drug.

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Compliance Marketing Drugs Pharma Companies 52

Drug Discovery World

OCTOBER 3, 2022

The seminars will include high profile speakers from pharma and biotech covering topics such as The Lab of the Future is Now, Data Handling and Choosing the Right Informatics System, The Sustainable Lab and The Remote Lab: Is This the Future? Product Manager, SPT Labtech. Making improvements to digitisation is a two-stage problem.

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Drugs Scientist Bioinformatics Medicine 52

The Pharma Data

MARCH 7, 2022

Cas9 binds and uses RNA as an address-tag. The system allows scientists, by synthesizing a specific “address-tag” RNA, to bring Cas9 to a precise location in genome and therefore cut and splice genes at specific sites. Cas9 is the protein used in the gene editing process called CRISPR.

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Protein Gene Genome Genomics 52

XTalks

OCTOBER 12, 2022

Perfusion is the passage of fluid through the lymphatic system or the circulatory system to an organ or tissue, and it typically refers to the delivery of blood to a capillary bed in tissue. The other option is to tag just one of the feeder vessels to the liver, but that does not capture the full blood flow in the liver.”.

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Clinical Trials Clinical Trials Trials Drugs 93

Drug Discovery World

JUNE 14, 2023

We have now our lead product in a Phase I/II study, which is a HER-2 directed tag T cell product for patients with HER-2 positive solid tumours. We know the immune system is there to naturally keep cancer cells at bay, so to be able to harness this therapeutically would be a great opportunity.

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pharmaphorum

NOVEMBER 16, 2022

However, R&D efforts into biological medicine have moved into the ascendency in recent times, as the treatments often offer targeted therapy and better outcomes. While this is of tremendous benefit to patients, it provides a headache to the pharma industry and to healthcare systems. However, with a price tag of €1.58

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Roots Analysis

SEPTEMBER 13, 2023

These molecules can be conjugated with various modalities, such as haptens, enzymes, isotopes, fluorescent tags, carrier proteins, polymers, particle conjugates and photoreactive molecules. These conjugates lead to elucidation of complex biological processes via signal amplification and high biological specificity.

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Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Kielczewska will present: ‘Discovery of antibody-based therapeutics to challenging targets: Platform considerations’.

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Engineer Antibody Protein In-Vivo 52

Drug Discovery World

NOVEMBER 13, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Protein Antibody Engineer Scientist 59

XTalks

JANUARY 19, 2024

There is a small but real risk of extravasation as well as a known systemic effect with intravenous administration. At the crux of radiobiological considerations are the 5Rs of radiobiology (listed below), which describe the biological response of cells and tissues to radiation.

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DNA Radiology FDA Approval Development 66

XTalks

NOVEMBER 24, 2022

“Gene therapy for hemophilia has been on the horizon for more than two decades,” said Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research (CBER). The company also said the price does not reflect anticipated discounts that it will offer for the therapy, including value-based agreements with commercial payers.

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Gene Therapy Gene FDA Approval Genetics 52

Drug Discovery World

OCTOBER 21, 2022

As we gain deeper understanding of normal biological processes as well as diseases, researchers and clinicians are increasingly seeking to analyse as many cellular parameters as possible to unravel their complexity. Peer reviewed publications are a good resource to understand expected biological expression levels.

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Reagent Antibody Drugs Protein 52

XTalks

MARCH 22, 2023

One reason innovation costs more today than it did in the early 2000s is because of the rising number of large biologic drugs in development requiring specialized manufacturing conditions. In addition, nearly half of all new drugs launched between 2020 and 2021 came with a price tag of $150,000 per year, or more.

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Life Science Drugs FDA Approval Vaccination 97

XTalks

FEBRUARY 11, 2021

After several such Nobel Prize snubs for female scientists, 2020 saw the Nobel Prize in Chemistry go to a female scientist duo for the first time for their revolutionary discovery of the CRISPR-Cas9 gene editing system. Through the radioactive labels, they were able to track which of the two, DNA or protein, was injected into the bacteria.

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Genetics DNA Genome Genomics 119

The Pharma Data

MAY 15, 2021

I have spent over 7 years in the medical and biological sciences. Web Beacons are tags that can monitor the behavior of a user visiting the Website or sending an e-mail. You may continue to receive such communications until our system completes the processing of your request.

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The Pharma Data

MAY 4, 2021

Panzyga (immune globulin intravenous [human] ifas 10% liquid preparation) — In February 2021, Pfizer announced that the FDA approved the supplemental Biologics License Application (sBLA) for Panzyga to treat adult patients with a rare neurological disease of the peripheral nerves called chronic inflammatory demyelinating polyneuropathy (CIDP).

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Pharma Marketing Network

JUNE 8, 2020

I started my career in consulting implementing systems inside of a couple dozen different hospitals and then I went on to find Microsoft’s healthcare partner ecosystem. Thanks for coming on the podcast and if you wouldn’t mind, could tell us a little bit about yourself. Dave (HR): Sure. Thanks for having me on.

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