Scienmag

APRIL 16, 2021

– April 16, 2021 – Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Credit: Dotted Yeti LA JOLLA, CALIF.

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Scienmag

MARCH 17, 2021

An international collaboration between Great Ormond Street Hospital, the UCL GOS Institute for Child Health and Harvard Medical School has shown that the beneficial effects of gene therapy can be seen decades after the transplanted blood stem cells has been cleared by the body.

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Scienmag

MAY 11, 2021

An international team of researchers at Great Ormond Street Hospital (GOSH), and University of California, Los Angeles (UCLA) have developed a gene therapy that successfully treated 48 out of 50 children with a form of severe combined immunodeficiency that leaves them without an immune system.

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Gene Therapy Gene Development Research 73

Scienmag

OCTOBER 26, 2020

Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus. The pro-viral and anti-viral […].

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Gene Research Gene Therapy Allergies 74

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

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Scienmag

OCTOBER 25, 2020

Jänne New results from early clinical trials of a drug that targets a cancer-causing mutation in the KRAS gene have shown that it can shrink tumours and is well-tolerated by patients. Latest results from KRYSTAL-1 early clinical trial of adagrasib (MRTX849) Credit: Pasi A.

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Scienmag

OCTOBER 29, 2020

USF Health-led TEDDY analysis focuses on development of multiple distinct autoantibodies targeting insulin-producing cells, from initial autoimmunity to symptomatic type 1 diabetes Credit: Courtesy of USF Health TAMPA, Fla.

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pharmaphorum

FEBRUARY 16, 2022

She received a cord blood transplant to treat the AML, receiving stem cells carrying a genetic mutation (CCR?5/?32) Having a third functional cure of HIV nevertheless does give pointers to how a more widely applicable cure might be developed in the future, for example using gene-editing drugs to introduce CCR5?32

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Gene Editing Research Gene Genetics 67

The Pharma Data

AUGUST 7, 2020

As the pharma industry stands firm in its commitment to advance the sector to fight Covid-19, news has emerged from the European Commission who intend to streamline the development of therapies using genetically modified organisms to treat Covid-19. Regenerative medicine and advanced therapies thriving despite Covid-19 disruption.

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XTalks

NOVEMBER 30, 2023

More Investigational Therapies for HIV Are on the Way American Gene Technologies, a pioneering biotech company headquartered in Rockville, Maryland, has released promising results from its Phase I trial of AGT103-T, a gene therapy designed for individuals with chronic HIV disease.

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XTalks

NOVEMBER 6, 2020

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We BacTRL Gene Therapy Platform.

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XTalks

JULY 26, 2021

Those who seek shorter ingredient lists and cleaner labels may object to plant-based meat due to the many additives and genetically modified proteins that tend to be crucial components of its formulation. For example, the Allergen Bureau indicated a possible connection between pea protein and peanut allergies. FDA Regulation.

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Scienmag

DECEMBER 13, 2020

In this type of therapy, T cells, a type of white blood cell, are collected from a patient’s blood and subjected to genetic engineering to produce T cells carrying a synthetic molecule termed chimeric antigen receptor (CAR) […].

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Genetic Engineering Engineer Genetics Allergies 95

Scienmag

FEBRUARY 1, 2021

According to a study published in Frontiers in Immunology, the reason is their genetic heterogeneity and lack of proportional representation in the Brazilian bone marrow bank Credit: Diogo Meyer A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National (..)

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Scienmag

NOVEMBER 25, 2020

First and corresponding author Dr Lucy van Dorp (UCL Genetics […]. The analysis of virus genomes from over 46,000 people with COVID-19 from 99 countries is published today in Nature Communications.

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Scienmag

OCTOBER 9, 2020

Findings could lay the foundation for the development of effective therapeutic and malaria vaccine strategies, which has largely been hindered by a lack of understanding of the host immune response Credit: Aissatou Diawara Abu Dhabi, UAE, October 9, 2020: The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers (..)

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The Pharma Data

FEBRUARY 22, 2021

Gene editing investments advance agriculture with improved food quality, higher yield, and improved crop nutrition. Gene editing is the key to better solutions and greater choices for farmers and consumers around the world. In crop science that means a transformative opportunity to improve yield and simplify harvesting for farmers.

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Scienmag

OCTOBER 12, 2020

Mouse immune study gives pointers for development of vaccines and immune therapies Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

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XTalks

DECEMBER 20, 2023

The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy. Bayer’s Astepro (azelastine), an over-the-counter medication for cold, flu and allergies, led the pack in the first half of 2023 with 7.4 billion ad impressions.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

Roots Analysis

AUGUST 31, 2023

According to a study, around 20,000 genes are present in the human body, all of which interact with the nutrients in the food, either directly or indirectly. Nutritional DNA testing helps in identifying foods that might lead to allergies or intolerance in an individual. Figure below presents an overview of nutrigenomics.

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Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

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Scienmag

JULY 14, 2021

Scientists report that the alternative-splicing regulator NSrp70 influences immune T cell development Credit: Gwangju Institute of Science & Technology T lymphocytes, or T cells, are immune cells with diverse roles in building the body’s immunity. How does one particular cell type fight against a host of different pathogens?

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Scienmag

JUNE 20, 2021

Researchers shed light on a potential intervention that could make tumors responsive to modern-day immunotherapies Credit: Mei Huang, PhD BOSTON – Researchers from Massachusetts General Hospital (MGH) have discovered a biological mechanism that transforms cells exposed to carcinogens from environmental factors like smoking and ultraviolet light (..)

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Scienmag

NOVEMBER 24, 2020

Credit: Salk Institute LA JOLLA–(November 24, 2020) Salk Professors Susan Kaech and Alan Saghatelian have been named 2020 Fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the journal Science.

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Scienmag

JANUARY 6, 2021

Research team determines that the “Immune only” focus of current research must be updated to better understand autoimmune diseases such as type 1 diabetes and multiple sclerosis Credit: Indiana Biosciences Research Institute Indianapolis, Ind.

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Research Allergies Gene Genetics 60

Scienmag

FEBRUARY 11, 2021

MUSC Hollings Cancer Center researcher finds loss of STING in recipient dendritic cells increases GVHD severity Credit: MUSC Hollings Cancer Center MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

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Research Gene Therapy Allergies Gene 53

Scienmag

OCTOBER 19, 2020

Garrido, CNIO The sophisticated human immune system has evolved to become an effective protection system against a great number of diseases, cancer being one of them. The immune system recognises and destroys cancer cells using a monitoring process called immunological surveillance.

Dermatology 52

Dermatology Allergies Gene Genetics 52

Scienmag

APRIL 19, 2021

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

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Gene Medicine Research Allergies 44

Drug Discovery World

AUGUST 1, 2023

They are a promising approach for the treatment of genetic drivers of disease.” AstraZeneca’s non-alcoholic steatohepatitis (or ‘NASH’) study is a prime example of the value of ASOs 2. Though some genetic mutations are harmful, others can be protective.

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The Pharma Data

JULY 8, 2021

This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Ann Allergy Asthma Immunol. World Allergy Organization (WAO). EMJ Allergy Immunol. J Allergy Clin Immunol. Explor Res Hypothesis Med. 2019;4:35-38. Eur Respir J.

Allergies 52

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Drug Discovery World

FEBRUARY 20, 2023

At the start of the year, a study sponsored by the US National Institute of Allergy and Infectious Diseases (NIAID) proved that an additional dose of a Covid-19 vaccine is safe in adults who had previously received a full regimen of an approved vaccine.

Drug Trials 52

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The Pharma Data

MAY 13, 2021

The REAL problem lies in the fact that most of the foods we eat today have been Genetically Modified. food is “A food in which the gene from one species has been forced into the DNA of another species and the process itself creates all sorts of unpredicted side effects.”. A better definition of a G.M.O. When lab rats were given G.M.O.

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The Pharma Data

NOVEMBER 9, 2020

This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. 10 World Allergy Organization (WAO). EMJ Allergy Immunol. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. 11 Busse WW.

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Drug Discovery World

NOVEMBER 9, 2023

Advances in discovery and engineering of antibodies for non-cancer targets This session will feature a range of presentations which include: Joshua Tan, PhD, Chief, Antibody Biology Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, on: ‘Discovery of broadley-neutralising antibodies against Coronaviruses’.

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XTalks

DECEMBER 24, 2020

From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. CRISPR Gene Editing Inventors Win Nobel Prize.

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XTalks

SEPTEMBER 14, 2020

These companies include Moderna, a US biotech company which has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID), Oxford University who has partnered with AstraZeneca, and Johnson & Johnson, Merck and Pfizer.

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