Pharmaceutical Technology
JANUARY 19, 2023
AOC 1020 has been designed for the treatment of the underlying cause of FSHD, which is caused by the abnormal expression of a gene known as double homeobox 4 or DUX4. Avidity Biosciences’ AOC 1020 is intended to reduce the DUX4 mRNA and DUX4 protein expression in muscles in these patients.
Pharmaceutical Technology
JUNE 4, 2023
Adeno-associated virus vectors, alcohol dehydrogenase compositions, and antibody serum stabilisers are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are anti-influenza antibody compositions and anti-interleukin-1, which are now well established in the industry.
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The Pharma Data
SEPTEMBER 2, 2021
In mice, an antibody directed against this factor was able to slow the growth of metastatic tumors.Blood vessels produce growth factor that promotes metastases. ” With a particular focus on the lung, the researchers performed global gene expression analyses of the metastatic niche.
Drug Discovery World
AUGUST 3, 2022
Over the years, a range of different CPPs have been developed, including natural translocating proteins through to newly-designed computer-prediction sequences 3. This is a common reaction within peptide chemistry and it has been approved by regulatory authorities for various antibody-drug conjugates 4. cells, such as diabetes.
XTalks
MARCH 22, 2021
The biotech acquisition will also see Takeda getting Maverick’s TAK-280 (MVC-280), an immunotherapy designed to treat patients with B7H3-expressing solid tumors which is expected to enter the clinic later this year. The biotech acquisition deal includes Five Prime’s prime asset bemarituzumab, which is a first-in-class anti-FGFR2b antibody.
Drug Discovery World
NOVEMBER 15, 2022
Applications: The ability to synthesise longer, accurate DNA sequences opens up a vast array of application possibilities: generating CRISPR libraries, in situ hybridisation probes, antibody libraries, vaccines, and so on, along with the ability to engineer metabolic pathways, microbes, and plants. .
Drug Discovery World
OCTOBER 17, 2023
Today, spatial omics technologies enable imaging-based identification of cells in their native tissue context while simultaneously detecting hundreds of RNAs or tens of protein markers in the same cells. Analysing spatial changes during disease progression or treatment response is key to fully understand pathologies.
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