Delveinsight

JULY 26, 2021

Often the bacteria develop antibiotic resistance to certain drugs, leaving it non-effective for the usage the second time in the case of recurrence of the infection that occurs in approximately 30-35% of the uUTI cases, therefore, leaving a serious dearth of the new antibiotics. coli bacteria called FimH.

Marketing 93

Marketing Bacteria Vaccination Vaccine 93

Roots Analysis

OCTOBER 16, 2023

DNA cloning refers to the process of generating multiple copies of a particular DNA segment. DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence.

DNA 40

DNA Gene Protein In-Vitro 40

Drug Discovery World

FEBRUARY 6, 2024

Technologies like artificial intelligence (AI), machine learning (ML) and robotics/automation are enabling researchers to process enormous data sets and conduct preclinical investigations in record time, speeding up the process and offering greater accuracy. Universities are also using these digital technologies to advance their research.

Marketing 69

Marketing Medicine Genome Genomics 69

The Pharma Data

OCTOBER 19, 2020

Caris’ collaborative network focused on expanding the application of precision medicine in oncology supports Winship’s enterprising approach to research leading to transformative discoveries in cancer care and treatment. IRVING, Texas and ATLANTA , Oct. Winship is one of 32 U.S. Curran, Jr. , FACR, FASCO.

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

XTalks

FEBRUARY 11, 2021

Much of the fundamental groundwork for genetics and genomic research was laid in the 20 th century, with significant contributions from women scientists, some of whom worked during times when acceptance of female researchers was not widespread. Here is a profile of some of those brilliant women who helped shape genetics research.

Genetics 119

Genetics DNA Genome Genomics 119

Drug Discovery World

APRIL 30, 2024

Whilst research into mRNA has been ongoing for decade, interest has sparked in recent years and research has begun to expand into areas of vaccinology, infectious diseases and other indications. Its job is to carry coding information that is essential to the translation and processing of functional proteins.

RNA 52

RNA Protein Vaccination Vaccine 52

Drug Discovery World

OCTOBER 11, 2023

Alexander Fleming, the discoverer of penicillin, warned, as early as 1945, against the overuse of antibiotics, suggesting it would select for resistant bacterial species 3 – in fact, penicillin-resistant bacteria were identified before penicillin was approved for use 1,4. Bacterial resistance has since returned as a major issue.

Bacteria 59

Bacteria Development Scientist Protein 59

Drug Discovery World

APRIL 25, 2024

According to Grand View Research, the global cell line development market was valued at $4.81 Grand View Research states that the market for cell lines is currently bolstered by the fact that the majority of biopharma companies use cell lines to synthesise recombinant monoclonal antibodies and proteins.

Development 59

Development Protein In-Vivo Life Science 59

Roots Analysis

AUGUST 31, 2023

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Further, the expression of any gene is dependent on the rate at which it is transcribed into mRNA and translated into proteins. When activator binds to the operon, it either speeds up or permits gene expression.

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Gene Gene Therapy Gene Expression Regulation 40

Drug Discovery World

MAY 2, 2023

Steve Wowk , VP, Business Unit and General Management of Integrated DNA Technologies, shared with DDW the value of CRISPR-Cas9 in drug discovery. Some of the most important breakthroughs in pharmaceutical research were adapted from naturally occurring phenomena. The gRNA is accompanied by the Cas9 enzyme responsible for cutting DNA.

Genome 52

Genome Genomics Gene DNA 52

XTalks

FEBRUARY 11, 2021

The drugmaker is targeting various steps in the manufacturing process, beginning right at the DNA stage, which is required as the template from which the mRNA for the SARS-CoV-2 spike protein in the vaccine is made. coli bacteria. The bacteria are grown in large vats, with the process taking two weeks.

Manufacturing 52

Manufacturing Vaccination Vaccine DNA 52

The Pharma Data

JANUARY 21, 2021

Researchers at Washington University School of Medicine in St. The test valuates mitochondrial DNA levels. When mitochondrial DNA, normally found inside cells, in the mitochondria, spills into the bloodstream, it signals that a particular type of violent cell death is occurring. The research was conducted in mice and humans.

Research 52

Research DNA Hormones Vaccination 52

Drug Discovery World

AUGUST 10, 2022

But decades of research led to improvements in cancer therapy, centred around the idea that one’s immune system could aid in treatment. Their continued promise has led to an exponential increase in research on their utility, function, risks, and potential benefits. Developing the first CAR T cell therapy.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

Drug Discovery World

MAY 4, 2023

The magic bullet was the drug, while the specific mark it would reach in the syphilis causing bacteria to eliminate the disease was the drug target. The drug target for Penicillin is a protein that helps bacteria to synthesise its cell wall. Salvarsan was soon overtaken by the Penicillin antibiotics.

Medicine 52

Medicine Protein Drugs Bioassay 52

Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Years of development and fast-paced research have continued to unlock its potential, expanding how CRISPR can be used to treat, detect, and prevent common diseases such as cancer and Covid-19.

DNA 98

DNA Genome Genomics RNA 98

Roots Analysis

OCTOBER 16, 2023

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. Membrane Filters: Membrane filters are typically used for sterilization and removal of smaller impurities such as bacteria and viruses. are used to remove any residual bacteria, viruses, or endotoxins.

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Bacteria Production Contamination Protein 40

pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. These technologies directly sequence single molecules of DNA in real time, often without the need for amplification.

Genome 106

Genome Genomics Medicine Gene 106

XTalks

DECEMBER 22, 2021

RNA, and its protein-generating form messenger RNA (mRNA) discovered in 1961 , has quickly transitioned from being an obscure, finicky molecule that is difficult to work with, to becoming a significant cornerstone of therapeutic innovation in pharma and biotech. percent, according to a report by BCC Research. RNA in the Making.

Life Science 98

Life Science RNA Vaccination Vaccine 98

XTalks

AUGUST 2, 2023

We delve into the driving forces behind their successes and shed light on the groundbreaking research that has earned them a place among the elite in the pharmaceutical arena. The monoclonal antibody targets CD20, a protein found on the surface of B lymphocytes (B cells). The FDA approved the drug over a decade ago in September 2009.

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Sales Manufacturing FDA Approval Life Science 98

XTalks

DECEMBER 24, 2020

The novel coronavirus behind the pneumonia-like disease was first isolated by Chinese researchers in early January and its genomic sequence was released on January 10. Researchers isolated the virus from nasopharyngeal and oropharyngeal samples from the infected patient and characterized its sequence and replication properties.

Life Science 111

Life Science Vaccination Vaccine Gene 111

The Pharma Data

OCTOBER 14, 2020

AOP anticipates new opportunities in Austria as a hub for research and business. The new services have been developed to support pre-clinical research by optimizing hiPSC-derived cell culture, while providing high-quality electrophysiological data acquisition and analysis from physiologically relevant human cell models.

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Clinical Trials Clinical Trials Manufacturing Trials 52