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Key early steps in gene expression captured in real time by CSU researchers

Scienmag

Capturing how RNA polymerase enzymes kick off transcription On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function.

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New cellular atlas maps out healthy and cancerous breast tissue

Scienmag

The research, which relied on expertise spanning from breast cancer biology through to bioinformatics, measured gene expression in single cells taken from healthy women and cancerous breast tissue, including […].

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How big data analytics can make personalised care a reality

Drug Discovery World

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

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FAIR Game: making data work harder in the race to market 

Drug Discovery World

For pharma and biotech companies – whether working on small or large molecule drugs, or cell and gene therapies – this means empowering scientists with better and faster data management approaches, best practices, and leading technologies so they can pinpoint new molecules and formulations and modify existing ones more easily and quickly.

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What to expect from SLAS Europe 2023

Drug Discovery World

Additionally, Dr Gianni will share insights on the use of these new tools in target validation and how they might revolutionise the drug discovery paradigm.

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Democratising proteomics for cancer and beyond

Drug Discovery World

Whilst the cause of DIPG isn’t known, the disease is characterised by specific mutations in genes coding for histone proteins – a family of basic proteins which can associate with DNA due to their positive charges. BMC Bioinformatics. These mutated proteins then reprogramme the epigenome, from which the cancer develops. “We

Protein 52
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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

If you want to order gene-length sequences, rather than short oligos for PCR, the waiting times are around two or three weeks at least. Modern advances in DNA synthesis, however, have made it possible to leverage gene-to- antibody production platforms where input candidate DNA sequences can be turned into purified antibodies.

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