Scienmag

JUNE 9, 2021

Researchers from CRAG and IRTA find the gene that determines Japanese plum skin colour due to the presence or absence of anthocyanins, a group of plant antioxidant pigments with health-promoting effects Credit: CRAG-IRTA The presence and accumulation of the antioxidant pigment anthocyanin dictates fruit hue in plums, and the synthesis of this compound (..)

Gene 89

Gene Research Bioinformatics Production 89

pharmaphorum

AUGUST 10, 2021

The three-year project – led by respiratory medicine expert Dr Timothy Hinks from the Oxford University Respiratory Medicine Unit – will use whole-genome sequencing of around 500 patients with severe asthma, comparing their gene sequences with control subjects who don’t have asthma. Dr Timothy Hinks.

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Gene Sequencing Bioinformatics Gene Genome 116

Scienmag

OCTOBER 5, 2020

Road trips result in the first shattering gene found in a wild population ST. LOUIS, MO — For years, Elizabeth (Toby) Kellogg, PhD, member and Robert E.

Gene 70

Gene Research Bioinformatics Production 70

pharmaphorum

JULY 5, 2022

It can be caused by exposure to loud noises – including prolonged use of earbuds at high volumes – as well as cancer treatment, illnesses, genetic mutations, or aging. An estimated 1.57

In-Vivo 98

In-Vivo Bioinformatics Genetics Licensing 98

Scienmag

JANUARY 13, 2021

International Ukraine Genetic Diversity Project finds a quarter of the genetic variation in Europe, dramatically increasing information on population diversity and medical genetic variation Credit: Oakland University Today, the largest study of genetic diversity in Ukraine was published in the open science journal GigaScience.

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Genome Genomics Genetics Research 98

Drug Discovery World

APRIL 18, 2023

Among individuals who consented to whole-exome sequencing and were identified as carriers of predisposition genes for hereditary breast and ovarian cancer (HBOC) or Lynch syndrome, 39.2% would not have qualified for genetic screening under current guidelines, according to results from the Tapestry clinical trial presented at AACR 2023 today.

Genetics 52

Genetics DNA Research Bioinformatics 52

pharmaphorum

JULY 20, 2022

The two organisations have previously collaborated on the creation of three cancer therapeutics companies, including bacterial delivery system developer Neobe therapeutics, oncolytic virus therapy company Stratosvir, and bioinformatics specialist Enedra.

Research 84

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Scienmag

DECEMBER 16, 2020

15, 2020 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become. Comparative analysis of human and animal coronaviruses strains implicates miR1307 PHOENIX, Ariz.

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Scienmag

APRIL 27, 2021

Credit: Nigel Michki Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

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Scienmag

MAY 27, 2021

Cellular proteins get their marching orders from genetic instructions encoded in DNA, whose sequences are first copied and made […].

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Scienmag

JANUARY 29, 2021

In 2017, the Nobel Prize in Physiology or Medicine went to three scientists who uncovered the molecular mechanisms that control the circadian rhythm, otherwise known as the “wake-sleep” cycle.

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Gene Scientist Medicine Research 69

XTalks

SEPTEMBER 28, 2020

The test is based on the detection of actionable genes – genes with known driver mutations that can be targeted by an approved therapy (or investigational therapies in clinical trials). The panel of genes in the test only include known NSCLC-associated genes, making the test specific to the disease. Personalized Approach.

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Gene DNA Life Science Genotype 105

Scienmag

NOVEMBER 25, 2020

Credit: Photo: IPK Leibniz Institute/ Andreas Bähring In order to record all genetic information of an individual, its genome must be completely decoded. But to understand the genetic information of the entire barley species, much more […].

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Scienmag

MAY 19, 2021

Credit: John Innes Centre Researchers have found the elusive genetic element controlling the elongated grains and glumes of a wheat variety identified by the renowned botanist Carl Linnaeus more than 250 years ago. Wheat, in bread, pasta, […].

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Genetics Production Research Bioinformatics 79

Scienmag

APRIL 23, 2021

This can be helpful in the study of rare genetic defects, among other things. A new VR platform enables the display of huge amounts of data. Credit: Sebastian Pirch, published in Nature Communications 2021. Networks offer a powerful way to visualize and analyze complex systems.

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Scienmag

JUNE 14, 2021

HOUSTON – (June 14, 2021) – In the two decades since the Human Genome Project mapped the entire human genome, improvements in technology have helped in developing updated reference genomes used for sequencing.

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Genome Genomics Genome Project Gene 40

Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Many tumours have a higher number of mutations due to a antiviral defence mechanism, the APOBEC system, which can accidentally damage DNA and cause mutations.

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Scientist DNA Genetics Medicine 53

Scienmag

JULY 1, 2021

Almost twenty years ago, the process of RNA silencing was discovered in plants, whereby small fragments of RNA inactivate a portion of a gene during protein synthesis.

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RNA Protein Research Gene 60

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

Genetics 52

Genetics Research Medicine Clinical Research 52

Drug Discovery World

OCTOBER 25, 2023

There are two main concepts underlying this impact; we’ve known for a few years now that people can have variable responses to the same medication and that these responses are largely based on an individual’s genetic makeup. NGS is becoming invaluable for treating individual cancer patients based on their tumour’s genetic makeup.

Bioinformatics 115

Bioinformatics Genetics RNA Drugs 115

Drug Discovery World

JULY 29, 2022

Scientists modelling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions – with implications for cancer treatments in humans.

Gene 52

Gene DNA Protein Genetics 52

XTalks

DECEMBER 13, 2023

3) Fulgent Genetics Compound annual growth rate: 260 percent Fulgent Genetics, headquartered in California, is a technology-driven company with a strong presence in clinical diagnostics and therapeutic development. The company achieved core revenues of $67 million, reflecting a remarkable 48 perecent year-over-year growth.

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Genetics Vaccination Vaccine DNA 111

Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

Drug Discovery World

JULY 26, 2023

With 100-fold the number of genes in the human genome 1 , this microbial collection is a rich genetic signature of clinical significance that we have only recently gained the tools to explore. Collectively, these systems biology bioinformatic puzzles often require partnerships to solve.

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Scienmag

MARCH 22, 2021

Credit: WEHI, Australia Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

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DNA Genome Genomics Research 96

Drug Discovery World

JULY 11, 2023

Advances in imaging technology, high-quality DNA and mRNA sequencing, and large-scale proteomics have yielded a plethora of data that can be analysed and cross- referenced to identify disease target genes or biological response signatures.

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Big Data Development Life Science Drugs 40

pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled.

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Genome Genomics Medicine Gene 113

Scienmag

AUGUST 21, 2020

Credit: Matt Verdolivo/UC Davis Humans are not the only species facing a potential threat from SARS-CoV-2, the novel coronavirus that causes COVID-19, according to a new study from the University of California, Davis.

Genome 91

Genome Genomics Scientist Bioinformatics 91

Scienmag

JULY 16, 2021

Credit: Vaughn Cooper PITTSBURGH, July 16, 2021 – For the first time ever, researchers from the University of Pittsburgh School of Medicine discovered that phages–tiny viruses that attack bacteria–are key to initiating rapid bacterial evolution leading to the emergence of treatment-resistant “superbugs.”

Research 73

Research Bacteria Medicine Bioinformatics 73

Scienmag

NOVEMBER 25, 2020

Credit: Rebecca Leber, UZH A variety of bread wheat that flourishes across Switzerland would remain just a poorly growing grass in India. This ability to adapt to regional climate conditions and environmental factors makes bread wheat the most commonly grown crop around the world. Its cultivation dates back around 8,000 years.

Bioinformatics 84

Bioinformatics Gene Genetics 84

Scienmag

MARCH 1, 2021

Screening for predictive factors of drug resistance and tailored therapies can improve outcomes in patients with refractory diffuse large B-cell lymphoma White blood cells or lymphocytes are the soldiers of our immune system that patrol the body via the lymphatic system.

Drugs 75

Drugs Bioinformatics Gene Genetics 75

Scienmag

SEPTEMBER 30, 2020

Researchers engineer RNA-targeting compounds that disable the pandemic coronavirus’ replication engine Credit: Scott Wiseman for Scripps Research JUPITER, FL – Sept.

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Engineer RNA Research Drugs 68

Scienmag

APRIL 20, 2021

A new study challenges the presumption that all South-Eastern-Bantu speaking groups are a single genetic entity. Almost 80% of South Africans speak one of the SEB family languages as their first language.

Genetics 61

Genetics Research Bioinformatics Gene 61

Scienmag

SEPTEMBER 4, 2020

ERC Starting Grants for Professor Dr Martina Hofmanová and Dr Toni Goßmann Credit: Photo: Bielefeld University /S. Jonek The European Research Council (ERC) has awarded ERC Starting Grants to two researchers from Bielefeld University. They will each receive 1.5 million euros for top-level research in their disciplines.

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Research Bioinformatics Gene Genetics 56

XTalks

NOVEMBER 7, 2022

Such information can reveal details about tumor staging, tumor progression, heterogeneity, gene mutations and clonal evolution. Dr. Bahassi explained that technological advances in genetic sequencing of cfDNA have enabled liquid biopsies and led to marked increase in the detection of therapeutically-targetable mutations.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

Biobanking 41

Biobanking Medicine Genome Genomics 41

Drug Discovery World

APRIL 21, 2023

SLAS Student Poster Award The SLAS Student Poster Award recognises innovative research by students, graduate students, post- doctoral associates and junior faculty (less than four years in first academic appointment) who are chosen to present a poster during SLAS Europe 2023.

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Doctors Doctor Genetics In-Vitro 52