Scienmag

MAY 5, 2021

Study published in JAMA Cardiology Credit: UIC/Jenny Fontaine A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

Cardiology 53

Cardiology Genetics Gene Research 53

Scienmag

APRIL 28, 2021

In a world first study of 390,435 people, University of South Australia researchers found causal genetic evidence that cardio health […].

Genetics 52

Genetics Research Cardiology Gene 52

Scienmag

NOVEMBER 18, 2020

— Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. ROCHESTER, Minn. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease ?

Genetics 40

Genetics RNA Protein Research 40

Scienmag

APRIL 20, 2021

Researchers at Penn Medicine uncover more genetic mutations that predispose women to peripartum cardiomyopathy, with implications for the future of increased genetic testing PHILADELPHIA– Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), (..)

Genetics 45

Genetics Development Medicine Research 45

The Pharma Data

OCTOBER 27, 2021

Appointment further strengthens Board scientific capabilities, including in genetics which is central to GSK’s R&D approach. Dietz MD, Professor of Genetic Medicine at The Johns Hopkins University School of Medicine in the United States, will join the Board of the Company as a Non-Executive Director.

Genetics 52

Genetics Medicine Cardiology Scientist 52

Scienmag

SEPTEMBER 7, 2020

Credit: Felix Petermann, MDC Hundreds of innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare.

Medicine 58

Medicine Research Bioinformatics Allergies 58

Scienmag

JUNE 3, 2021

Credit: Unsplash A dash of milk could make all the difference to a healthy heart as new research from the University of South Australia finds that people who regularly consume milk have a lower risk of heart disease.

Genetics 95

Genetics Research Cardiology Medicine 95

Scienmag

AUGUST 31, 2020

Sophia Antipolis, France – 31 Aug 2020: Losing weight could prevent or even reverse diabetes, according to late breaking research presented today at ESC Congress 2020.1 In 2019, approximately 463 million people worldwide had diabetes, of which the vast majority (around 90%) was type 2 diabetes.2

Genetics 72

Genetics Research Cardiology Medicine 72

The Pharma Data

OCTOBER 22, 2020

22, 2020 — Pregnancy can increase the risk of a rare, dangerous heart condition called aortic dissection, researchers report. Researchers analyzed data from 29 women who were unexpectedly hospitalized for aortic dissection while pregnant. 14 in the journal JAMA Cardiology. THURSDAY, Oct. Patients require lifesaving care.

Cardiology 52

Cardiology Hormones Genetics Research 52

Scienmag

DECEMBER 3, 2020

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say. Eugene Chen, M.D., […].

Gene Editing 41

Gene Editing Gene DNA Genetics 41

Scienmag

FEBRUARY 17, 2021

In a world first genetic study, researchers from the Australian Centre for Precision Health at the University of South Australia found that that long-term, […].

Genetics 65

Genetics Research Cardiology Medicine 65

Scienmag

DECEMBER 3, 2020

In a randomized, controlled clinical trial, researchers found that patients who received genetic test results about the side effects of cholesterol-lowering medications did not have worse outcomes after one year A person’s genetic make-up can influence whether they might experience side effects from certain medications.

Clinical Trials 44

Clinical Trials Clinical Trials Trials Genetics 44

Scienmag

NOVEMBER 19, 2020

Precise treatment leads to resolution of patient’s debilitating symptoms and complete remodeling of her lymphatic system Philadelphia, November 20, 2020–Researchers at Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, (..)

Research 67

Research Cardiology Gene Genetics 67

Scienmag

OCTOBER 15, 2020

Benoit Bruneau and Katie Pollard study DNA folding to identify the genetic causes of congenital heart disease Credit: Photo: Gladstone Institutes SAN FRANCISCO, CA–October 15, 2020–The National Institutes of Health (NIH) has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, (..)

DNA 54

DNA Genetics Scientist Research 54

Scienmag

OCTOBER 22, 2020

Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe.

Research 41

Research Scientist Medicine Cardiology 41

Scienmag

JANUARY 14, 2021

14, 2021 — Adults who smoke or who are genetically predisposed to smoking behaviors are more likely to experience a serious type of stroke called subarachnoid hemorrhage (SAH), according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. […].

Genetics 46

Genetics Research Cardiology Medicine 46

The Pharma Data

AUGUST 30, 2021

Wilson disease is a rare and progressive genetic condition in which the body’s pathway for removing excess copper is compromised. ALXN1840, a potential new once-daily, oral medicine, demonstrated approximately three times greater copper mobilisation than SoC. Wilson disease. 1 It affects one in 30,000 live births in the US.

Trials 52

Trials Genetics Cardiology Medicine 52

The Pharma Data

JANUARY 5, 2021

For the study, the researchers reviewed medical records of close to 119,000 kids, aged 4 to 17, who were treated at Texas Children’s Hospital in Houston more than once between 2011 and 2016. The defects range from mild to severe and sometimes require immediate or multiple surgeries. Of those, 1,164 had congenital heart disease.

Cardiology 52

Cardiology Doctors Doctor Genetics 52

The Pharma Data

DECEMBER 8, 2020

The company’s commercial priorities are three-fold: (1) Initially focusing its commercial efforts on rare diseases within its prolific neurology and cardiology franchises (2) pioneer new markets where there are no available treatments (3) create new standards of care where there has been a lack of innovation to optimize patient care.

Medicine 52

Medicine RNA Production Marketing 52

Delveinsight

DECEMBER 29, 2020

X-linked myotubular myopathy (XLMTM) is a rare genetic neuromuscular disorder and leads to muscle weakness, respiratory failure, and early death. The ASPIRO trial is a two-part, open-label ascending dose study, and is examining the safety and preliminary efficacy of AT132 in children with XLMTM younger than five years old. The post A USD 4.2

Trials 52

Trials Drugs Hormones Radiology 52

Scienmag

JUNE 17, 2021

Researchers from University of Tsukuba, Japan, collaborating with scientists from Germany, develop a mouse model for restrictive cardiomyopathy and uncover the underlying mechanisms of the disease Ibaraki, Japan – Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that (..)

Scientist 70

Scientist Development Research Cardiology 70

Scienmag

NOVEMBER 9, 2020

Preeclampsia-related gene expression in the placenta may correlate with vitamin D status during pregnancy, report researchers from the Medical University of South Carolina. Credit: Medical University of South Carolina According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies.

Gene 52

Gene Gene Expression Research Cardiology 52

Scienmag

SEPTEMBER 24, 2020

The findings were published this month in Scientific Reports by Université de Montréal professor Christian Deschepper, director of the Experimental Cardiovascular Biology research unit of […].

Gene 60

Gene Research Cardiology Genetics 60

Scienmag

AUGUST 7, 2020

Research points to potential to reduce triglyceride levels without the risk of unpleasant and serious side effects in the intestines and liver Credit: Image is courtesy of Navid Marvi.

Research 52

Research Cardiology Genetics Medicine 52

Scienmag

OCTOBER 7, 2020

What could researchers learn by following hundreds of […].

Protein 52

Protein Scientist Research Cardiology 52

Scienmag

NOVEMBER 25, 2020

New research led by Robert E. Gerszten, MD, Chief of the Division of Cardiovascular Medicine at Beth Israel Deaconess Medical Center (BIDMC) […].

Genetics 49

Genetics Research Medicine Cardiology 49

The Pharma Data

OCTOBER 28, 2020

28, 2020 — There may be a positive causal relationship between elevated birth weight and risk for future atrial fibrillation in adulthood, according to a study presented at the annual Great Wall International Congress of Cardiology, held virtually from Oct. WEDNESDAY, Oct. The genome-wide association study included 321,223 individuals.

Cardiology 40

Cardiology Genetics Genome Genomics 40

Scienmag

FEBRUARY 7, 2021

Beer-Sheva, Israel…February 8, 2021 – A new discovery by researchers from Ben-Gurion University of the Negev (BGU) and its affiliated Soroka University Medical Center shows that medical cannabis may reduce blood pressure in older adults.

Research 67

Research Medicine Clinical Trials Clinical Trials 67

WCG Clinical

MAY 22, 2023

As one respondent said: “Appropriate representation of ethnic groups and sex are critical to the scientific validity of research findings, and their absence can lead to false conclusions. 4,5 In fact, lack of representation in clinical trials compromises generalizability of research findings. Current Problems in Cardiology.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Cardiology 52

The Pharma Data

NOVEMBER 4, 2020

Progressed European regulatory review and commercial preparations : Continued to support regulatory review of VASCEPA by the European Medicines Agency (EMA) with the expectation of an early 2021 approval of VASCEPA for commercial sale in Europe. The design of the REDUCE-IT study was published in March 2017 in Clinical Cardiology.

Sales 40

Sales Production Cardiology Marketing 40

The Pharma Data

SEPTEMBER 15, 2020

I am proud of the truly transformational science that our research and clinical teams are bringing to the fight against disease, as well as the unprecedented speed with which we are advancing our clinical programs in the battle against COVID-19. Internal Medicine. THERAPEUTIC AREAS OF FOCUS. approval in 2021. and -50.4%

Gene Therapy 52

Gene Therapy Vaccination Vaccine Trials 52

The Pharma Data

MAY 13, 2021

Experimental Diabetes Research. Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions. The Yale Journal of Biology and Medicine. Journal of strength and conditioning research / National Strength & Conditioning Association. 2014.09.007.

Insulin 52

Insulin Production Hormones Medicine 52