Scienmag

JUNE 11, 2021

In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells PHILADELPHIA – Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell.

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DNA RNA Containment Research 58

Scienmag

OCTOBER 4, 2020

CHICAGO – Researchers have identified genetic mutations that appear to protect women from severe bleeding after childbirth, a leading cause of maternal death. DNA, which carries genetic information in cells, contain biological instructions. A genetic mutation, which is a permanent […].

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Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials.

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Scienmag

SEPTEMBER 14, 2021

The term ‘DNA’ immediately calls to mind the double-stranded helix that contains all our genetic information. But the individual units of its two strands are pairs of molecules bonded with each other in a selective, complementary fashion.

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DNA Gene Containment Genetics 40

Scienmag

OCTOBER 22, 2020

When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again. Poop contains very precise information about the prey […]. For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species.

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DNA Containment Scientist Bioinformatics 54

Scienmag

NOVEMBER 15, 2021

Cell biologists track this process by observing chromosomes—structures made of DNA that contain the genetic material of an organism. Cell division is an important process that underlies biological growth and repair. However, their analysis is still […].

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DNA Containment Genetics Research 83

Scienmag

APRIL 23, 2021

Credit: Gemma Lofthouse An international team of researchers led by the University of Bergen has uncovered how organisms from crops to corals may avoid deadly DNA damage during evolution. Our cells, and those of animals, plants and fungi, contain compartments that produce chemical fuel.

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DNA Containment Research Genetics 89

Drug Discovery World

DECEMBER 20, 2023

Relatively little has been known about the genetics or biology of this metastatic site until now. BCLM genetically distinct from primary breast tumour For this study, researchers at the Breast Cancer Now Toby Robins Research Centre at the ICR analysed liquid biopsies, which contain circulating tumour DNA (ctDNA).

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Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. The vaccine also contains other inactive ingredients such as cholesterol.

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Drug Discovery World

JANUARY 26, 2023

Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could be exploited by new treatments. The major difference was cell size.

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Scienmag

JULY 14, 2021

Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles Credit: Mindy Takamiya/Kyoto University iCeMS Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles. The findings, by scientists at Kyoto […].

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DNA Containment Scientist Research 97

Scienmag

APRIL 8, 2021

This full assembly may contain clues to ape and human divergence; certain immune, brain and heart disorders; and other biomedical questions Credit: Kendra Hoekzema The full assembly of human chromosome 8 is reported this week in Nature.

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Gene DNA Containment Genetics 90

STAT News

OCTOBER 12, 2022

From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

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DNA Containment Scientist Medicine 144

FDA Law Blog

DECEMBER 8, 2022

labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. Most notably, the draft guidance clarifies that the following food products are subject to the allergen labeling requirements: Bulk containers (e.g., Other technical labeling matters.

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Genetic Engineering Containment Cosmetics Protein 59

Drug Discovery World

DECEMBER 5, 2022

Scientists have unlocked key insights into virus evolution, revealing new information that could help develop treatments for a wide variety of genetic diseases. . Some have even been successfully harnessed as gene therapy vectors for the treatment of genetic diseases. .

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Gene Therapy Gene Genetic Disease Genetics 52

XTalks

NOVEMBER 6, 2020

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We

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pharmaphorum

OCTOBER 19, 2022

The dark genome – a loose term that covers non-coding regions of the genome that are capable of regulating the expression of genes, previously rather inaccurately referred to as junk DNA – is increasingly being explored by biopharma companies for new drug targets. Dr Danuta Jeziorska.

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Drug Discovery World

AUGUST 14, 2023

The EU, however, defines all gene therapies as “recombinant genes transferred directly into the body” and cell therapies as those that insert genetic modification into a cell and the cell becomes the drug product. If not properly planned for, the regulatory requirements can delay market entry and patient access to these therapies.

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Gene Therapy Marketing Gene DNA 52

Roots Analysis

OCTOBER 16, 2023

DNA cloning refers to the process of generating multiple copies of a particular DNA segment. DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence.

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The Pharma Data

JANUARY 4, 2021

The UC Santa Barbara research uses a method that addresses not only antibiotic overuse, but also the containment of genetically modified organisms (GMOs). “If

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Bacteria Engineer Genetics Genetic Engineering 52

pharmaphorum

AUGUST 5, 2021

Critical cellular processes including DNA replication and translation cannot occur without functional-specific proteins. Whereas targets like receptors contain an obvious ligand-binding site for drug molecules to interact with, PPIs comprise a more complex structure. Current challenges and conventional approaches in targeting PPIs.

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The Pharma Data

NOVEMBER 27, 2020

Nasdaq:RYTM), a biopharmaceutical company aimed at developing and commercializing therapies for the treatment of rare genetic diseases of obesity, announced today that the U.S. With this approval, Imcivree becomes the first-ever FDA approved therapy for these rare genetic diseases of obesity. BOSTON, Nov.

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The Pharma Data

MARCH 7, 2022

The IGA results in the equivalent genotype (genetic make-up) and short-hair coat trait seen in some conventionally bred cattle, known as a “slick” coat. This is the FDA’s first low-risk determination for enforcement discretion for an IGA in an animal for food use. Solomon, D.V.M., director of the FDA’s Center for Veterinary Medicine.

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Genome Genomics Production Marketing 52

XTalks

FEBRUARY 11, 2021

This has ushered in a new era of genomics that is fostering rapid, detailed and personalized insights into human genetics. Xtalks is celebrating the International Day of Women and Girls in Science with a special overview of notable female scientists who have made revolutionary contributions to the field of genetics. Rosalind Franklin.

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Genetics DNA Genome Genomics 119

Pharmaceutical Technology

JUNE 14, 2023

Basic human traits such as eye and hair colour are determined by our DNA. However, more immeasurable characteristics such as personality, behaviour, and even intelligence are all influenced by genetics to varying degrees. metres of supercoiled DNA contained within its nucleus. Each human cell has 1.8

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The Pharma Data

JANUARY 21, 2021

Session: Expanding Targetable Genetic Alterations in NSCLC Mini Oral Session Date and Time: January 31, 2021, 14:20 SGT (January 30, 2021 10:20 p.m. PT) Presentation Number: MA11.04. PT) Presentation Number: MA13.07. Access to the presentations is available to members of IASLC and can be found here: [link].

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Clinical Trials Clinical Trials Licensing Licensing 52

The Pharma Data

JANUARY 11, 2021

Neither of the two vaccines approved in the United States — made by Pfizer-BioNTech and Moderna — contains the live virus. While the blueprint is a genetic code, it never enters the nucleus of the cells. “That means it never converts into DNA,” Dr. M. said in a health system news release.

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The Pharma Data

OCTOBER 18, 2020

(NASDAQ:CDXC) today highlighted a new study published in The European Molecular Biology Organization Journal looking at the effect of nicotinamide riboside (NR) on maintaining telomeres, the protective regions at the end of DNA strands. Telomeres are “caps” at the end of chromosomes that protect DNA from getting worn away as cells replicate.

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DNA Scientist Genetic Disease Research 52

XTalks

DECEMBER 13, 2023

3) Fulgent Genetics Compound annual growth rate: 260 percent Fulgent Genetics, headquartered in California, is a technology-driven company with a strong presence in clinical diagnostics and therapeutic development. The company achieved core revenues of $67 million, reflecting a remarkable 48 perecent year-over-year growth.

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Genetics Vaccination Vaccine DNA 111

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA). These tumor-derived entities are used to derive genomic and proteomic data.

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Clinical Trials Clinical Trials Trials FDA Approval 98

Roots Analysis

AUGUST 31, 2023

Gene switches can be regulatory proteins or specific DNA sequences that act to either switch on or off the expression of a gene. Basic Components of Gene Switch Gene switches are composed of noncoding DNA sequences and transcription factors. These genetic switches assist transcription factors in binding to the promoter region.

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Drug Discovery World

NOVEMBER 15, 2022

Rapid and accurate DNA synthesis . Conventional DNA synthesis, typically used for making sequences such as primers, employs phosphoramidite chemistry, a method that was developed in the 1980s and is still considered the gold standard for DNA synthesis. .

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DNA Drugs Antibody Engineer 98

Drug Discovery World

FEBRUARY 28, 2023

The LSK114 protocol allows for any fragment length of DNA to be sequenced, which can range from cell-free DNA to amplicons to any length DNA fragments, from 200 base pairs to more than 100kb. Sequencing native, long fragments of DNA is beneficial to generate more comprehensive insights into the genome – which often contain methylation, repetitive (..)

Genome 52

Genome Genomics DNA Genetics 52

Roots Analysis

MARCH 1, 2023

Genotoxicity testing refers to the evaluation of detrimental effects of chemical or physical agents on the genetic processes and related hereditary material of living cells. Mechanism of Genotoxicity / Mutagenicity The interaction of genotoxins / mutagens with the structure of DNA causes damage to the genetic material.

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Genotoxicity DNA Genetics Bacteria 52

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells through epigenetic editing without altering the genetic sequence itself. Epigenetic Editing with CRISPR. pyogenes dCas9.

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DNA Gene Gene Silencing Genome 98

XTalks

FEBRUARY 4, 2021

Bernard, executive vice president for research and chief research officer at Vanderbilt University Medical Center, shared his experience in helping set up a DNA and clinical data resource called BioVU. The project began in 2004, in the early days of biobanking for DNA, says Dr. Bernard, and has grown tremendously since.

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Research Biobanking Drugs Genome 98

The Pharma Data

NOVEMBER 24, 2020

Lynparza exploits tumour DNA damage response (DDR) in cells/tumours harbouring a deficiency in homologous recombination repair (HRR), such as mutations in BRCA1 and/or BRCA2 , to selectively kill cancer cells. Germline genetic testing in prostate cancer – further enrichment in variant histologies? Prostate cancer statistics.

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