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Researchers teach AI to tailor artificial DNA for drug development

Drug Discovery World

Now we have succeeded in designing our own DNA that contains the exact instructions to control the quantity of a specific protein,” said Aleksej Zelezniak. . The AI designs synthetic DNA, where it is easy to modify its regulatory information in the desired direction of gene expression. .

DNA 52
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Biotech founder arrested in US amid murder-for-hire investigation

pharmaphorum

Gümrükcü is a specialist in gene expression profiling in stem cells, and has been working on ways to deliver stem cell transplants to treat cancer without the need for high-dose induction chemotherapy to destroy the patient’s bone marrow. .” ” If convicted, they face mandatory life in prison or the death penalty.

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Nucleome raises £37.5m to shine light on ‘dark genome’

pharmaphorum

The dark genome – a loose term that covers non-coding regions of the genome that are capable of regulating the expression of genes, previously rather inaccurately referred to as junk DNA – is increasingly being explored by biopharma companies for new drug targets.

Genome 57
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Symvivo’s Oral COVID-19 Vaccine Enters Clinical Trials

XTalks

DNA vaccines designed using the platform consist of a combination of an advanced gene expression plasmid (pDNA) with gene(s) of interest, and a probiotic bacterium to deliver the vaccine directly to the gut, where it binds to intestinal epithelial cells.

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Fulcrum Therapeutics Announces Pricing of Public Offering of Common Stock – Jan 20, 2021

The Pharma Data

Fulcrum’s proprietary product engine identifies drug targets which can modulate gene expression to treat the known root cause of gene mis-expression. Forward-Looking Statements. Actual results may differ materially from those projected or implied in these forward-looking statements.

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Cell-penetrating peptides as a delivery system for oligonucleotides

Drug Discovery World

These peptides typically contain up to 30 amino acids and can be cationic, amphipathic or both. This work shows great potential for new treatment options for diseases caused by an aberrant gene expression in pancreatic ?-cells, Here, Bachem explores the science behind this approach. What are cell-penetrating peptides?

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Burning Rock Announces an Exclusive in-Licensing of a Risk Stratification Test for Early Stage Lung-Cancer Patients from Oncocyte in China

The Pharma Data

Oncocyte has also launched DetermaIO , a gene expression test that identifies patients more likely to respond to checkpoint inhibitor immunotherapies, for research and pharma clinical trial use. This press release contains forward-looking statements. Safe Harbor Statement.