Drug Discovery World

OCTOBER 16, 2023

The United Kingdom has established itself as a hub for drug discovery expertise worldwide. There is a range of reasons why this area has become focal point for drug discovery, one of which is the fact that it encompasses the University of Oxford and the University of Cambridge, two of the oldest and most prestigious universities in the world.

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Drugs Life Science Gene Therapy Genome 75

pharmaphorum

JANUARY 24, 2023

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.

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Drug Discovery World

JANUARY 26, 2024

Dr Bentwich will present on ‘ How artificial intelligence and patient-on-a-chip are improving drug development ’ on Tuesday 6 February at 3pm. His presentation will explore the impact of Quris-AI’s Bio-AI platform in the field of drug development.

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Pharmaceutical Technology

JUNE 5, 2023

Earlier this year, Sun Pharmaceutical Industries , one of India’s largest generic drug producers, reported a major cybersecurity breach , impacting its business operations. Pharma companies around the world have also faced similar threats , some of which have impacted national security and public health.

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Compliance Regulation Pharmacy Genome 276

pharmaphorum

OCTOBER 12, 2022

AstraZeneca has teamed up with DNA sequencing giant Illumina on a new programme that will use artificial intelligence to find new targets for drug discovery by sifting through vast arrays of data generated from “omics” studies.

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Genome Genomics DNA Drugs 64

pharmaphorum

AUGUST 10, 2020

The data mining tool will be used to try to unearth some of the many unknowns with the virus, using next-generation sequencing (NGS) to see how the genome of SARS-CoV-2 changes over time, along with patient genetic information, results of lung and CT scans, and other clinical data.

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Genetics Genome Genomics Vaccination 136

pharmaphorum

OCTOBER 13, 2020

UK biotech e-therapeutics has a new CEO, with executive chairman and former Silence Therapeutics chief Ali Mortazavi chosen to spearhead the next stage in the company’s development into gene silencing and other areas. He said: “These big pharma companies have every type of technology available to them.

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Gene Silencing Gene RNA Genome 100

pharmaphorum

OCTOBER 18, 2022

US-based Tempus has built a precision medicine platform – powered by artificial intelligence and machine learning – that sifts through a large library of anonymised patient data, including results of clinical, molecular, and genomic testing. The two companies have been working together for some time.

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Drug Discovery World

MAY 22, 2023

Cell therapy, RNA technology, antibody drug conjugates and AI/machine learning are among the key areas of investment for pharma, according to a new report. Clarivate’s ‘Biopharma Dealmaking in 2023’ report examines how pharma companies are replenishing their pipelines as many face a steep patent cliff.

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RNA Pharma Companies Antibody Life Science 52

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. Sangamo CEO Sandy Macrae told us how his company is being cautious about the hype and finding ways to be financially viable in an emerging space. billion in funding.

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Drug Discovery World

OCTOBER 4, 2022

DDW Editor Reece Armstrong explores some of the trends that will be featured in sessions throughout ELRIG Drug Discovery 2022 and the news behind them. Automated systems have become a prominent feature throughout drug discovery, helping scientists save time and assisting in reproducible experiments for more verifiable results.

Gene Therapy 52

Gene Therapy Drugs Gene Manufacturing 52

Camargo

NOVEMBER 11, 2020

When the FDA requires a product’s labeling to include a boxed warning (also called a “black box warning” because the text is surrounded by black border), the potential market value of the drug often drops severely. Presumably, Antares’ long-established 90-person urology sales force can achieve pull-thru of this drug product.

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Development Bioequivalency Generic Drugs Production 242

Drug Discovery World

FEBRUARY 6, 2024

As AI-designed drugs start to enter large-scale clinical trials, DDW’s Diana Spencer investigates how new digital tools are reinventing and reshaping drug discovery for the future. Quris-AI, which combines patient-on-a-chip, AI and real-time nano-sensing technologies to predict the safety and efficacy of drug candidates.

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Marketing Medicine Genome Genomics 69

Drug Discovery World

DECEMBER 27, 2023

You can also find The Drug Discovery World Podcast on Spotify , Google Play and Apple Podcasts. These are just some of the words that come to mind when talking about not just the drug discovery sector, but the lives of those working in and around it. He speaks about this drug discovery journey here. Developing. Listen here.

Clinical Trials 69

Clinical Trials Clinical Trials Drugs Development 69

Drug Discovery World

JANUARY 21, 2024

Technology is increasingly important to drug discovery. Advances in this area are having a positive effect on both the commercial success of drug discovery and development organisations, as well as benefitting the health and wellbeing of the global population. Is pharma’s commercial model dying?

Protein 52

Protein Vaccination Vaccine Development 52

pharmaphorum

APRIL 19, 2021

But it has also faced criticism from pharma companies that say it undervalues medicines – patients in the country were denied access to the expensive cystic fibrosis drug Orkambi for four years because of a pricing row with NICE and the NHS.

Medicine 88

Medicine Pharma Companies Genome Genomics 88

pharmaphorum

DECEMBER 9, 2022

The new graduates – selected out of 75 applicants in a hotly contested application process – are working on a diverse array of digital health platforms including remote patient monitoring techniques, biomarkers, drug discovery and analytics tools, data annotation platforms, therapeutic-area data models, and novel RWE datasets.

Life Science 52

Life Science DNA Genome Genomics 52

pharmaphorum

OCTOBER 20, 2021

The trial – which will be supported by pharma company Eisai and Ionian University in the US – will see if the test can identify people who have mild cognitive impairment (MCI) due to Alzheimer’s disease. ” The post Eisai-backed trial will assess Altoida’s digital test for early Alzheimer’s appeared first on.

Trials 78

Trials Genome Genomics Bioinformatics 78

pharmaphorum

OCTOBER 28, 2020

Data defines modern therapeutics, but this is almost uniquely confined to the clinical trial stages of drug development. Identifying, recruiting, retaining and monitoring patients during this part of the cycle is estimated to cost pharma US$19 billion a year as companies seek to harvest patient experiences.

Medicine 119

Medicine Pharma Companies Vaccination Vaccine 119

pharmaphorum

NOVEMBER 27, 2022

A group representing pharma companies selling precision therapies for cancer has called for a change to the way genomic testing is done in Scotland, to make sure patients get access to targeted drugs. The post Genomic testing ‘should be offered to all cancer patients in Scotland’ appeared first on.

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Genome Genomics Genetics Medicine 104

pharmaphorum

SEPTEMBER 18, 2020

But although it was dubbed a “dangerous game”, some companies came out on top… On 6th April 1999, two companies with similar science-based cultures and a shared vision of the pharmaceutical industry came together to form what’s now considered as one of the top ten pharma companies in the world: AstraZeneca.

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Pharma Companies Sales Vaccination Vaccine 116

pharmaphorum

APRIL 7, 2022

” Now, the aim is to layer in genomics surveillance using Ares’ next-generation sequencing (NGS) expertise, improving the monitoring of resistant pathogens and making sure that antibiotics are prescribed wisely. “AMR, which is now estimated to directly account for nearly 1.3

Bioinformatics 52

Bioinformatics Genetics Genome Genomics 52

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. The tide has been turning in the worlds of diagnostics and drug development. A recent flurry of announcements indicates increasing interest and trust from major public health organisations in the power of genomics.

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Genome Genomics Bioinformatics Genetics 52

Drug Discovery World

AUGUST 8, 2023

DDW’s Megan Thomas takes a deeper look into why India is ramping up drug discovery research, and explores the country’s innovation hubs of interest. According to a report by Deloitte, globally India is the third largest in the world by volume and 11th by value, comprising over 3,000 pharma companies and 10,500 manufacturing facilities 2.

Research 52

Research Drugs Genome Genomics 52

Pharmaceutical Technology

FEBRUARY 13, 2023

Although recently approved drugs can treat seizures more safely, they do not treat the comorbidities that patients experience. Several biotech companies and researchers are now exploring medical devices and gene therapies to address not just common forms of epilepsy, but also rare conditions such as Dravet Syndrome.

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Research Gene Gene Therapy Genome 264

pharmaphorum

AUGUST 9, 2022

AI could address the most significant issue in drug discovery, finds Ben Hargreaves, and also offers the potential to use tissue samples to create precision medicine for specific patient groups. An area that offers hope to accelerate an understanding of cancer and speed up drug development is artificial intelligence. Patient focus.

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Drugs Doctors Doctor Pharma Companies 111

Drug Discovery World

JANUARY 26, 2023

According to research from Deloitte 1 , the average ROI in R&D for global pharma companies fell to just 1.2% The modernisation of R&D models could be key to reducing spend on new drugs, a point that Deloitte makes about the need to transform the clinical trials process. the industry experienced in 2021.

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Development Drugs Clinical Trials Clinical Trials 98

Delveinsight

DECEMBER 15, 2020

Gannex received US FDA fast track designation for its NASH drug, ASC42 an FXR Agonist. Gannex Pharma has received Fast Track designation approval from FDA for its drug candidate ASC42 for non-alcoholic steatohepatitis (NASH). Sold under the name Jakafi, it is FDA-approved for the treatment of polycythemia vera (PV) in adults.

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Vaccination Vaccine Gene Therapy Gene 54

pharmaphorum

MARCH 28, 2022

Built under a government tender, AION Labs comprises four large international pharma companies – AstraZeneca , Merck, Pfizer , and Teva – and another core partner, the Israel Biotech Fund. Yerushalmi states there are numerous ways AI can support the pharma process – from clinical trials to patient stratification.

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Pharma Companies Antibody Protein Development 98

XTalks

DECEMBER 20, 2023

As we step into 2024, the life sciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables. Regulatory bodies are also taking note of the applications of AI in drug development.

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Life Science Gene Editing Development Clinical Trials 119

XTalks

AUGUST 18, 2020

SalivaDirect, a saliva-based COVID-19 test that was tested among players of the National Basketball Association (NBA), has been given emergency use authorization (EUA) by the US Food and Drug Administration (FDA). The EUA comes after Yale partnered with the NBA to study the efficacy of the saliva-based test.

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FDA Approval Reagent RNA Genome 90

pharmaphorum

OCTOBER 5, 2021

The next level is to make medical data available for research purposes through digital platforms, such as through the work of our portfolio company BC Platforms , who integrate clinical and genomic data of millions of patients globally. Funding radical innovation.

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Drug Discovery World

NOVEMBER 15, 2022

Anita Ramanathan outlines four synthetic biology approaches that are improving and accelerating drug discovery. . It has made its way into almost every aspect of drug discovery, whether it’s exploring basic biology, modelling diseases, identifying and validating targets, or performing drug screens. .

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DNA Drugs Antibody Engineer 98

XTalks

DECEMBER 13, 2023

Now, let’s delve into the list of the top ten fastest growing biotech companies in 2023, ranked by their compound annual growth rate (CAGR). These companies were identified through The Americas’ Fastest-Growing Companies 2023 list by the Financial Times. million and $38.8 million, respectively, as compared to $17.6

Genetics 111

Genetics Vaccination Vaccine DNA 111

pharmaphorum

SEPTEMBER 1, 2020

Another military man in the drugs business was Edward Robinson Squibb, who as a naval doctor during the Mexican-American war of 1846–1848 threw the drugs he was supplied with overboard due to their low quality. This investment fuelled the development of drugs to come over the coming decades.

Medicine 145

Medicine Insulin Pharmacy Drugs 145

pharmaphorum

NOVEMBER 12, 2020

The mid-sized pharma group has also signed a collaboration with Florida, US-based Lacerta Therapeutics , adding more AAV capsids – well established as a staple for delivering gene therapy sequences – as well as another gene therapy candidate. The post UCB revs up its gene therapy drive with Handl acquisition appeared first on.

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Gene Therapy Gene Manufacturing Contract Manufacturing 52

pharmaphorum

SEPTEMBER 7, 2022

But our drug development processes are not perfect. Pharma can always move faster, whilst prioritising patient health. And, at the heart of this, pharma cannot escape from the reality that the industry is operating with deep historical biases in collecting health data – from ethnic, to socio-economic, to gender biases.

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