Genetics, Research and Scientist - Clinical Research Informer

Scientists Discover a Genetic Variant That Seems to Limit HIV Infection

AuroBlog - Aurous Healthcare Clinical Trials blog

AUGUST 13, 2023

A tiny fraction of people are naturally resistant to HIV infections, and scientists want to understand why. Now an international team of researchers has discovered a new genetic variant in people of African ancestries that appears to restrict HIV replication after an infection sets in.

Genetics

Genetics Scientist Research Clinical Trials

Leveraging Genetic Testing for Enrolling Rare Disease Trials

Worldwide Clinical Trials

JANUARY 24, 2024

Written By: Derek Ansel, MS, CCRA, Executive Director, Therapeutic Strategy Lead, Rare Disease Given that 80% of rare diseases have a genetic etiology, genetic implications should be addressed at the onset of a clinical program to support trial enrollment. One diagnostic example that I discussed in my presentation is autism.

Genetics

Genetics Trials Clinical Trials Clinical Trials

We’ve Discovered A Subtle Genetic Imbalance That May Drive Aging

AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 21, 2022

Scientists have found an extremely subtle twist in the genetics of aging cells, one that seems to make them increasingly less functional as time goes on.

Genetics

Genetics Gene Scientist Research

Researchers identify large genetic changes that contribute to dementia risk

Medical Xpress

MAY 8, 2023

Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer's dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale DNA changes, known as structural variants, by analyzing thousands of DNA samples.

Genetics

Genetics DNA Research Genome

Scientists expand entomological research using genome editing

Scienmag

JULY 22, 2022

Genome sequencing, where scientists use laboratory methods to determine a specific organism’s genetic makeup, is becoming a common practice in insect research.

Genome

Genome Genomics Scientist Research

STAT+: On the long road to treating Huntington’s genetic stutter, scientists return to overlooked clues

STAT News

NOVEMBER 30, 2022

The scientists sent the blood 950 miles east to Massachusetts General Hospital in Boston, to a tiny lab (recently converted from a storeroom) where a 28-year-old postdoc named James Gusella and his 23-year-old research technician, Rudolph Tanzi, got to work.

Genetics

Genetics Scientist DNA Gene

Scientists Create Synthetic Human Embryo Models in Major First

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 19, 2023

The research – first brought to wider attention by The Guardian – has prompted excitement about the potential for new breakthroughs in health, genetics, and treating disease. In a major scientific first, synthetic human embryo models have been grown in the lab, without any need for the usual natural ingredients of eggs and sperm.

Scientist

Scientist Genetics Research Clinical Trials

Why early participant engagement is now a top priority in genetic disease research

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. Giving participants something in return. with their priorities.

Genetic Disease

Genetic Disease Genetics Research Genome

Genetically engineered dendritic cells enhance lung cancer therapy

Drug Discovery World

APRIL 9, 2024

A study by researchers at the UCLA Health Jonsson Comprehensive Cancer Center in the US suggests that injecting engineered dendritic cells directly into cancerous lung tumours can help promote a stronger immune response.

Genetic Engineering

Genetic Engineering Engineer Genetics Immune Response

Japanese-European research team discovers novel genetic mitochondrial disorder

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

Genetics

Genetics DNA Genome Genomics

This Common Artificial Sweetener Can Break Down DNA, Scientists Warn

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 8, 2023

As DNA holds the genetic code controlling how our bodies grow and are maintained, that’s a serious problem that […] The artificial sweetener sucralose (marketed as Splenda) is widely used and found in products like diet soda and chewing gum.

DNA

DNA Scientist Genetics Production

Scientists engineer safe, virus-resistant E coli for research

Drug Discovery World

MARCH 21, 2023

In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. Genetic engineering The findings build on earlier efforts by genetic engineers, which involved genetically reprogramming E.

Engineer

Engineer Genetic Engineering Scientist Bacteria

Genetic and molecular insights into dangerous tick bite-related meat allergy revealed

Scienmag

JULY 5, 2022

Scientists have revealed the genetic and molecular structure of key molecules linked to the sometimes life-threatening mammalian-meat allergy brought on by tick bites.

Allergies

Allergies Genetics Scientist Research

Study reveals how genetic mutations combine to cause blood cancer

Drug Discovery World

JANUARY 19, 2024

UK scientists have uncovered the interplay between cancer-driving genetic mutations and inherited genetic variants in a rare type of blood cancer. The study describes how inherited genetic variants can influence whether a spontaneous mutation in a particular gene increases the risk of developing this rare blood cancer.

Genetics

Genetics Gene DNA Development

Hong Kong pulls visa for ‘CRISPR babies’ scientist He Jiankui

STAT News

FEBRUARY 21, 2023

BEIJING — Hong Kong on Tuesday revoked a visa it granted to a Chinese scientist who set off an ethical debate five years ago with claims that he made the world’s first genetically edited babies, pulling it hours after he announced his research plans in the financial hub.

Scientist

Scientist Genetics Licensing Licensing

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Medical Xpress

NOVEMBER 22, 2022

Scientists at University of Florida (UF) Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored the health of neurons in the lab and rescued mice with the disease.

RNA

RNA Scientist Genetics Development

Scientists discover unique Cornish ‘falgae’

Scienmag

MARCH 30, 2021

Credit: Mark Milburn/Atlantic Scuba Red algae that grow in Cornwall’s Fal Estuary are genetically unique, new research shows. University of Exeter scientists studied the population genetics of Phymatolithon calcareum, a coralline red algal species that forms maerl beds in shallow coastal seas from Portugal to Norway.

Scientist

Scientist Genetics Research

Scientists develop mouse model to study mpox virulence

Medical Xpress

FEBRUARY 14, 2023

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have removed a major roadblock to better understanding of mpox (formerly, monkeypox).

Scientist

Scientist Development Allergies Genetics

COVID-19 case severity: How genetic differences leave immune cells at a disadvantage

Scienmag

NOVEMBER 19, 2021

LA JOLLA, CA—New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells. Credit: La Jolla Institute for Immunology LA JOLLA, CA—New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells.

Genetics

Genetics Scientist Research

Scientists discover a new genetic form of ALS in children

Scienmag

MAY 31, 2021

NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy Credit: Courtesy of the NIH/NINDS.

Genetics

Genetics Scientist Gene Manufacturing

Can genetic data be a magic bullet for drug R&D?

pharmaphorum

JANUARY 24, 2023

Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates. The logical extension to this kind of approach is treating individual patients, with their individual genetic makeup.

Genetics

Genetics Drugs Genome Project Biobanking

Discrimination lawsuit against HHMI spotlights barriers faced by scientists with disabilities

STAT News

APRIL 19, 2023

But after Cheung herself developed a genetic condition so rare it doesn’t have an official name, causing her to start losing her vision, HHMI decided to stop funding her. “I was asked to take a medical retirement,” Cheung told STAT. “I felt that I was being judged for having a disability.”

Scientist

Scientist Genetic Disease Genetics Research

Scientists prevent “exhaustion” in cancer-fighting T cells

Scienmag

JUNE 28, 2022

Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed “T cell exhaustion” by scientists. Now, researchers at Gladstone Institutes and Stanford University have revealed the genetic switches that get […].

Scientist

Scientist Genetics Research Medicine

Genetic sleuthing reveals endangered river dolphins in Asia as different species

Scienmag

MARCH 29, 2021

Tissue collection at NOAA Fisheries lab helps reveal genetic distinction Credit: Mansur/WCR Bangladesh New genetic analysis and years of painstaking research has revealed that one of the world’s most endangered marine mammals is actually two species rather than one, as scientists had long assumed.

Genetics

Genetics Genetic Analysis Scientist Research

Women in Science Who Have Paved the Way Forward in Genetics

XTalks

FEBRUARY 11, 2021

This has ushered in a new era of genomics that is fostering rapid, detailed and personalized insights into human genetics. Xtalks is celebrating the International Day of Women and Girls in Science with a special overview of notable female scientists who have made revolutionary contributions to the field of genetics.

Genetics

Genetics DNA Genome Genomics

Nobel Prize in medicine awarded for research into the evolutionary history of humankind

STAT News

OCTOBER 3, 2022

A Swedish scientist won the 2022 Nobel Prize in medicine or physiology on Monday for his groundbreaking research into the evolutionary history of humankind. Pääbo unlocked scientists’ understanding of how genes from these extinct relatives have been passed down to present-day humans.

Medicine

Medicine Contamination Research DNA

Clinical Scientist Jobs: The Steps to Succeed in This Role

XTalks

MAY 20, 2022

Do you possess laboratory skills, an analytical mindset and a penchant for research? If you enjoy working with biological samples and are enthusiastic about healthcare, a career as a clinical scientist might be just right for you. To start applying to clinical scientist jobs today, head over to the Xtalks Job Search platform.

Scientist

Scientist Life Science Clinical Research Doctors

Scientists identify new gene involved in autism spectrum disorder

Scienmag

DECEMBER 23, 2020

Forward genetics pinpoints gene linked to ASD involving severe speech impairment and opens door to search for more mutations, future treatments Credit: Photo taken by Brian Coats for UT Southwestern Medical Center DALLAS – Dec.

Scientist

Scientist Gene Genetics Research

Researchers uncover “genetic goldmine” underlying plant resilience in extreme desert environment

Scienmag

NOVEMBER 1, 2021

An international team of researchers has identified genes associated with plant survival in one of the harshest environments on Earth: the Atacama Desert in Chile. Their findings, published in Proceedings of the National Academy of Sciences (PNAS), may help scientists breed resilient crops that can thrive in increasingly drier climates.

Genetics

Genetics Research Gene Scientist

Rare genetic disease caused by mutations in protein that controls RNA metabolism

Scienmag

MAY 7, 2021

Credit: UPMC PITTSBURGH, May 7, 2021 – In a paper published today in Nature Communications, an international group of collaborators led by researchers at UPMC Children’s Hospital of Pittsburgh have identified a genetic cause of a rare neurological disorder marked by developmental delay and loss of coordination, or ataxia.

Genetics

Genetics Genetic Disease RNA Protein

BU researchers untangle the APOE4 gene, the most significant genetic risk factor for Alzheimer’s disease

Scienmag

JUNE 23, 2022

Scientists have discovered some genetic variants that increase the risk for developing Alzheimer’s; the most well-known of these for people over the age of 65 is the APOE ?4 (Boston)—Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8

Genetics

Genetics Gene Research Scientist

STAT+: Moderna expands CRISPR gene editing research with ElevateBio partnership

STAT News

FEBRUARY 22, 2023

The Cambridge biotech company announced Wednesday that it will partner with Life Edit Therapeutics to develop potentially permanent treatments for rare genetic diseases and other conditions. Life Edit is the North Carolina subsidiary of ElevateBio, a cell and gene therapy manufacturing firm in Waltham.

Gene Editing

Gene Editing Gene Genetic Disease Gene Therapy

UMaine researchers: Culture drives human evolution more than genetics

Scienmag

JUNE 2, 2021

In a new study, University of Maine researchers found that culture helps humans adapt to their environment and overcome challenges better and faster than genetics.

Genetics

Genetics Research Scientist

Helix web tool guides prostate cancer genetic testing

pharmaphorum

NOVEMBER 29, 2021

A web-based digital tool called Helix could help clinicians identify patients with prostate cancer who would benefit from genetic testing and counselling, according to researchers in the US. “Our digital solution, Helix, demonstrated promising results for clinical use,” write the researchers in the paper.

Genetics

Genetics Nurses Scientist Research

Researchers reverse the in vitro and in vivo effects of the mutation that causes Stormorken syndrome

Medical Xpress

MAY 16, 2023

Sometimes scientists arrive at new findings and discoveries by chance. They study gene variation and mutations that cause rare genetic diseases. A mutation is a permanent change in the genetic material. A mutation is a permanent change in the genetic material.

In-Vitro

In-Vitro In-Vivo Genetic Disease Genetics

Assay Development Scientist Jobs: What to Know About the Field

XTalks

OCTOBER 19, 2023

An assay development scientist combines deep biological and biochemical expertise with practical laboratory skills to develop tests that can answer specific biological questions or drive the drug discovery process. Related: Pharmaceutical Scientist Jobs: What to Know Before Applying What Does an Assay Development Scientist Do?

Scientist

Scientist Development Research Compliance

Regular Short Naps Could Be The Easiest Way to Reduce The Risk of Dementia

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 25, 2023

Scientists from the US, UK, and Uruguay analyzed data from 378,932 people aged 40 to 69 to see how those who are genetically ‘programmed’ to nap regularly fared cognitively […]

Genetics

Genetics Scientist Clinical Trials Clinical Trials

Inclusive new tool makes genomic research better reflect world’s diversity

Scienmag

MARCH 10, 2022

Scientists have developed a powerful, inclusive new tool for genomic research that boosts efforts to develop more precise treatments for many diseases by leveraging a better representation of the genetic diversity of people around the world.

Genome

Genome Genomics Research Scientist

#news #biotech Scientists uncover the underlying genetics that make flies champion fliers

BioTech 365

MARCH 18, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists uncover the underlying genetics that make flies champion fliers.Flies have developed excellent flying skills thanks to a set of complicated interactions between numerous genes influencing wing … Continue reading (..)

Genetics

Genetics Scientist Gene Development

Researchers speed identification of DNA regions that regulate gene expression

Scienmag

MAY 6, 2021

Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology–identifying the genetic ‘switches’ that regulate gene expression. Jude Children’s Research Hospital St. Credit: St.

Gene Expression

Gene Expression Regulation Gene DNA

Down syndrome research should look at the whole cell, not just the extra chromosome, scientists say

Medical Xpress

DECEMBER 1, 2022

Research on understanding the effect of extra chromosomes for conditions like Down syndrome typically involves examining what genes play a role in the symptoms of these conditions. However, researchers from Germany and the U.S. However, researchers from Germany and the U.S.

Research

Research Scientist DNA Genetics

Scientists create mouse avatars to treat multiple myeloma

Medical Xpress

MARCH 29, 2023

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

Scientist

Scientist Genetics Research Development

UCI scientists make leap forward for genetic sequencing

Scienmag

MARCH 11, 2022

March 11, 2022 — In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes DNA sequencing possible. Irvine, Calif.,

Genetics

Genetics Scientist DNA Research

Gentoo penguins are four species, not one, say scientists

Scienmag

NOVEMBER 3, 2020

Credit: Gemma Clucas Gentoo penguins should be reclassified as four separate species, say scientists at the Milner Centre for Evolution at the University of Bath, after analysing the genetic and physical differences between populations around the southern hemisphere.

Scientist

Scientist Genetics Research

Scientists Discover a Genetic Variant That Seems to Limit HIV Infection

Leveraging Genetic Testing for Enrolling Rare Disease Trials

Trending Sources

We’ve Discovered A Subtle Genetic Imbalance That May Drive Aging

Researchers identify large genetic changes that contribute to dementia risk

Scientists expand entomological research using genome editing

STAT+: On the long road to treating Huntington’s genetic stutter, scientists return to overlooked clues

Scientists Create Synthetic Human Embryo Models in Major First

Why early participant engagement is now a top priority in genetic disease research

Genetically engineered dendritic cells enhance lung cancer therapy

Japanese-European research team discovers novel genetic mitochondrial disorder

This Common Artificial Sweetener Can Break Down DNA, Scientists Warn

Scientists engineer safe, virus-resistant E coli for research

Genetic and molecular insights into dangerous tick bite-related meat allergy revealed

Study reveals how genetic mutations combine to cause blood cancer

Hong Kong pulls visa for ‘CRISPR babies’ scientist He Jiankui

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists discover unique Cornish ‘falgae’

Scientists develop mouse model to study mpox virulence

COVID-19 case severity: How genetic differences leave immune cells at a disadvantage

Scientists discover a new genetic form of ALS in children

Can genetic data be a magic bullet for drug R&D?

Discrimination lawsuit against HHMI spotlights barriers faced by scientists with disabilities

Scientists prevent “exhaustion” in cancer-fighting T cells

Genetic sleuthing reveals endangered river dolphins in Asia as different species

Women in Science Who Have Paved the Way Forward in Genetics

Nobel Prize in medicine awarded for research into the evolutionary history of humankind

Clinical Scientist Jobs: The Steps to Succeed in This Role

Scientists identify new gene involved in autism spectrum disorder

Researchers uncover “genetic goldmine” underlying plant resilience in extreme desert environment

Rare genetic disease caused by mutations in protein that controls RNA metabolism

BU researchers untangle the APOE4 gene, the most significant genetic risk factor for Alzheimer’s disease

STAT+: Moderna expands CRISPR gene editing research with ElevateBio partnership

UMaine researchers: Culture drives human evolution more than genetics

Helix web tool guides prostate cancer genetic testing

Researchers reverse the in vitro and in vivo effects of the mutation that causes Stormorken syndrome

Assay Development Scientist Jobs: What to Know About the Field

Regular Short Naps Could Be The Easiest Way to Reduce The Risk of Dementia

Inclusive new tool makes genomic research better reflect world’s diversity

#news #biotech Scientists uncover the underlying genetics that make flies champion fliers

Researchers speed identification of DNA regions that regulate gene expression

Down syndrome research should look at the whole cell, not just the extra chromosome, scientists say

Scientists create mouse avatars to treat multiple myeloma

UCI scientists make leap forward for genetic sequencing

Gentoo penguins are four species, not one, say scientists

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