pharmaphorum

OCTOBER 28, 2020

Claus Møldrup explores research showing that patients want their voice to be heard more by pharma, and asks what a truly effective feedback loop for medicines might look like. Pharma remains stubbornly closed to feedback, with potentially damaging consequences for the industry, healthcare systems and patients.

Medicine 119

Medicine Pharma Companies Vaccination Vaccine 119

Drug Discovery World

MAY 22, 2023

Cell therapy, RNA technology, antibody drug conjugates and AI/machine learning are among the key areas of investment for pharma, according to a new report. Clarivate’s ‘Biopharma Dealmaking in 2023’ report examines how pharma companies are replenishing their pipelines as many face a steep patent cliff.

RNA 52

RNA Pharma Companies Antibody Life Science 52

pharmaphorum

OCTOBER 18, 2022

One of the first actions by GSK’s recently appointed chief scientific officer, Tony Wood, has been to expand a partnership with Tempus aimed at improving the big pharma’s R&D productivity, starting with its cancer pipeline.

Production 52

Production Clinical Trials Clinical Trials Genome 52

Drug Discovery World

FEBRUARY 6, 2024

Companies leading the way There are a number of companies leading the charge in applying innovative technologies, particularly artificial intelligence (AI) and machine learning (ML), to the search for new medicines. Digital tech is also helping researchers to find target candidates for some of the most challenging disease areas.

Marketing 69

Marketing Medicine Genome Genomics 69

pharmaphorum

JANUARY 24, 2023

The cost of testing per human genome in 2006 was approximately $14 million , and in less than two decades, an average consumer-purchased genetic test costs $100. The same is becoming true for the healthcare industry, and one of the first major breakthroughs in the area was the 100,000 Genomes Project.

Genetics 92

Genetics Drugs Genome Project Biobanking 92

XTalks

DECEMBER 20, 2023

In 2024, pharma companies and emerging biotechs will improve candidate safety profiles and reduce off-target effects by exploiting predictive intelligence unlocked by AI,” she predicts. These companies are at various stages of research and clinical trials.

Life Science 119

Life Science Gene Editing Development Clinical Trials 119

Camargo

NOVEMBER 11, 2020

In November 2017, Foundation Medicine received approval for FoundationOne CDx , a genomic profiling test for solid state tumors, which paved the way for partnerships with pharma companies’ therapeutics. In 2019, Foundation Medicine and Bayer Healthcare Pharmaceuticals, Inc.

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Development Bioequivalency Generic Drugs Production 242

Drug Discovery World

JANUARY 21, 2024

Proximity-inducing drugs: Using technological innovation to build the next generation of medicine Simon Bushell, SVP of Molecular Discovery of Entact Bio, has over two decades of scientific and strategic leadership experience in drug discovery. Is pharma’s commercial model dying?

Protein 52

Protein Vaccination Vaccine Development 52

Drug Discovery World

OCTOBER 16, 2023

Indeed, this is bolstered by top tier universities like Newcastle University, which specialises in structure-based approaches for drug discovery, developing innovative technologies that support the identification of new medicines, and is well-established in cancer drug discovery. Government investment of £1.3

Drugs 75

Drugs Life Science Gene Therapy Genome 75

pharmaphorum

NOVEMBER 27, 2022

A group representing pharma companies selling precision therapies for cancer has called for a change to the way genomic testing is done in Scotland, to make sure patients get access to targeted drugs. The post Genomic testing ‘should be offered to all cancer patients in Scotland’ appeared first on.

Genome 93

Genome Genomics Genetics Medicine 93

XTalks

DECEMBER 13, 2023

Now, let’s delve into the list of the top ten fastest growing biotech companies in 2023, ranked by their compound annual growth rate (CAGR). These companies were identified through The Americas’ Fastest-Growing Companies 2023 list by the Financial Times.

Genetics 111

Genetics Vaccination Vaccine DNA 111

Drug Discovery World

DECEMBER 27, 2023

In this episode, Kelland shares what she means by the ‘next pandemic’, the lessons learnt from the Covid-19 pandemic, and the role of global health organisations and pharma companies going forward. Dr Pace discusses how precision medicine is already starting to influence standards in clinical trial design. Listen here.

Clinical Trials 69

Clinical Trials Clinical Trials Drugs Development 69

pharmaphorum

SEPTEMBER 18, 2020

But although it was dubbed a “dangerous game”, some companies came out on top… On 6th April 1999, two companies with similar science-based cultures and a shared vision of the pharmaceutical industry came together to form what’s now considered as one of the top ten pharma companies in the world: AstraZeneca.

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Pharma Companies Sales Vaccination Vaccine 116

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. Increasingly, major collaborative life sciences projects, like the Human Genome Project or Human Cell Atlas, are driving advancements and organisations – both public and private – are taking note.

Genome 52

Genome Genomics Bioinformatics Genetics 52

Delveinsight

DECEMBER 15, 2020

Gannex Pharma has received Fast Track designation approval from FDA for its drug candidate ASC42 for non-alcoholic steatohepatitis (NASH). The FTA designation will help the pharma company to advance its research and development in the NASH landscape and help its commercialization in the market.

Vaccination 54

Vaccination Vaccine Gene Therapy Gene 54

XTalks

OCTOBER 15, 2021

The lawsuit claims that Thermo Fisher is profiting off the stolen tissue samples, despite the broad publicity that Lacks’ story has received over the past decade and its link to a long tradition of discriminatory practices in medicine.

Vaccination 105

Vaccination Vaccine Gene Mapping Doctors 105

Drug Discovery World

OCTOBER 4, 2022

There’s no question that cell and gene therapies have emerged as some of the most promising and innovative medicines on the market. . With 3,633 advanced therapeutical medicinal products (ATMPs) currently in some form of clinical or pre- clinical development, the sector shows no signs of slowing down. Cell and gene therapies.

Gene Therapy 52

Gene Therapy Drugs Gene Manufacturing 52

Drug Discovery World

AUGUST 8, 2023

According to a report by Deloitte, globally India is the third largest in the world by volume and 11th by value, comprising over 3,000 pharma companies and 10,500 manufacturing facilities 2. Similarly, The Times of India says that branded generic medicines have “long fuelled India’s pharmaceutical exports” 4.

Research 52

Research Drugs Genome Genomics 52

pharmaphorum

DECEMBER 6, 2022

A few decades ago, gathering genetic data on the scale of the 100,000 Genomes Project would have been unthinkable – it was only in 2003 that the entire human genome was mapped. In 2018, the 100,000 Genomes Project completed its collection of data from 100,000 participants and the study of that collected information is still on-going.

Genome Project 95

Genome Project Research Genome Genomics 95

pharmaphorum

SEPTEMBER 1, 2020

Similarly, whilst GlaxoSmithKline’s origins can be traced back as far as 1715, it was only in the middle of the 19th century that Beecham became involved in the industrial production of medicine, producing patented medicine from 1842, and the world’s first factory for producing only medicines in 1859.

Medicine 145

Medicine Insulin Pharmacy Drugs 145

Drug Discovery World

JANUARY 26, 2023

The invasion of Ukraine by Russia was devastating, and its effects were felt throughout pharma as supply chains were disrupted and companies had to pause any operations they were pursuing in those countries, limiting access to medicines in both the near and long term. Despite this, innovation still occurred.

Development 98

Development Drugs Clinical Trials Clinical Trials 98

pharmaphorum

NOVEMBER 12, 2020

The mid-sized pharma group has also signed a collaboration with Florida, US-based Lacerta Therapeutics , adding more AAV capsids – well established as a staple for delivering gene therapy sequences – as well as another gene therapy candidate.

Gene Therapy 52

Gene Therapy Gene Manufacturing Contract Manufacturing 52

pharmaphorum

AUGUST 9, 2022

AI could address the most significant issue in drug discovery, finds Ben Hargreaves, and also offers the potential to use tissue samples to create precision medicine for specific patient groups. Of course, this is not the reality today but as advancements are made by companies such as Owkin and Exscientia, perhaps it could be.

Drugs 105

Drugs Doctors Doctor Pharma Companies 105

pharmaphorum

SEPTEMBER 7, 2022

For example, currently, most genomics studies are conducted in populations of European descent, whilst African ancestry populations, for example, show significantly greater genetic variation. Whilst this is an early area of research, pharma can turn the dial now. Only then can medicines work equally for all patients.

Clinical Trials 95

Clinical Trials Clinical Trials Trials Genetics 95

pharmaphorum

DECEMBER 15, 2022

With the bell then tolling within the House of Commons, Brine concluded that prevention and care were critical, and particularly future cancer care – getting ‘upstream’ of symptom-led early diagnosis with genomic medicine, despite the ‘billion ethical questions’ that go alongside that. Innovation adoption: a contact sport.

Life Science 90

Life Science Medicine Clinical Trials Clinical Trials 90

pharmaphorum

MARCH 30, 2021

Alexion is a somewhat unique pharma company in that it focuses almost entirely on rare diseases – and although this is an immensely challenging area to operate in, the company’s senior vice president of its international business, Camilla Harder Hartvig, says it provides an unparalleled “sense of mission”.

Genetics 110

Genetics Marketing Development Genome 110

Drug Discovery World

JANUARY 3, 2023

Most major pharma companies operate DEL platforms, and several service providers offer DEL capabilities to companies that outsource their DEL activities. Most commonly, DELs are used to supply high-quality starting points to medicinal chemistry projects for a specific biological target. cytokine-receptor disrupters).

DNA 52

DNA Protein Drugs RNA 52

Drug Discovery World

NOVEMBER 15, 2022

To accelerate drug development timelines, biotechs and pharma companies may choose to outsource some or all parts of antibody discovery and optimisation to DNA synthesis technology partners equipped with the tools and techniques to get reliable results faster. Engineering biosensors for specific functions .

DNA 98

DNA Drugs Antibody Engineer 98

Drug Discovery World

SEPTEMBER 7, 2022

AI has long been touted as a kind of new frontier in life sciences, something that when applied to its full potential, could fundamentally change the way pharmaceutical companies develop medicines. . Under the current model of discovering new medicines, scientists have to manually explore vast quantities of information.

Research 52

Research Scientist Clinical Trials Clinical Trials 52

The Pharma Data

OCTOBER 14, 2020

Prestige BioPharma – Singapore-based Prestige received a positive opinion from the European Medicines Agency Orphan Drug Commission (COMP) for its first-in-class anti-PAUF monoclonal antibody, PBP1510, for the treatment of pancreatic cancer. ERS Genomics – Ireland’s ERS Genomics signed an agreement with FASMAC Co., Ltd of Japan.

Clinical Trials 52

Clinical Trials Clinical Trials Manufacturing Trials 52

Pharmaceutical Technology

MARCH 20, 2023

Pharma companies and world health stand to benefit from new technologies, but it’s a tough time to be an investor – and an even tougher one for firms seeking investment. One significant growth area is the rise of genomics. Further rate hikes could be on the way this year.

Gene Therapy 225

Gene Therapy Genome Genomics Gene 225