Drug Discovery World

OCTOBER 3, 2022

The role of AI and automation in personalised medicine: How can AI help in the post drug discovery process. She completed her academic training with a post-doctoral career development fellowship in Protein Engineering at the MRC Laboratory of Molecular Biology in Cambridge, UK. The sustainable lab. in Chemistry and D.Phil.

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Genome Genomics Drugs Engineer 97

pharmaphorum

OCTOBER 11, 2022

Asked how he made the shift from working out the structure of proteins and how molecules bind to those proteins, to the founding of pharmaphorum and focusing on the digital space, his answer was clear: communication. As it turned out, pharmaphorum’s launch coincided with digital’s early permeation of the healthcare industry.

Pharma Companies 95

Pharma Companies Medicine Doctors Doctor 95

pharmaphorum

DECEMBER 21, 2020

Compared with many of the established names in pharma these companies are young upstarts but they have managed to achieve what other big names in the industry have failed to do and harness the power of mRNA to make medicine. In this case that is the “spike” protein seen on the surface of the coronavirus that it uses to invade host cells.

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Vaccination Vaccine Doctors Doctor 93

The Pharma Data

OCTOBER 23, 2020

23, 2020 — High levels of a protein that lubricates the knee joint may actually be a harbinger of impending joint disease, a surprising animal study suggests. “We know that if a person or animal doesn’t make that protein, they will develop devastating joint disease affecting all the major weight-bearing joints.”

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Protein Doctors Doctor Research 52

Drug Discovery World

SEPTEMBER 5, 2022

The discovery was made by researchers at Washington University School of Medicine in St Louis, Grenoble Alpes University in Grenoble in France, and The University of Texas MD Anderson Cancer Center in Houston. One of the challenges we will face is convincing doctors to go back to an old drug. This has not changed for 30 years.

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Protein Drugs Medicine Research 52

pharmaphorum

SEPTEMBER 17, 2020

The vaccine is based on a weakened virus that causes cold symptoms in chimpanzee, which causes an immune respone with genetic material coding for the spike protein found on the surface of the coronavirus. According to the World Health Organization, AZ’s vaccine is the most advanced in a list of 36 vaccines in clinical trials for COVID-19.

Vaccination 105

Vaccination Vaccine Trials Doctors 105

pharmaphorum

SEPTEMBER 16, 2020

The two antibodies chosen by Regeneron bind to the receptor binding domain of the virus’s spike protein, which it uses to bind with and infect healthy cells. RECOVERY is conducted by the Nuffield Department of Population Health in partnership with the Nuffield Department of Medicine.

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Drug Discovery World

NOVEMBER 1, 2022

“Generality is critical for automation, and thus making molecular innovation accessible even to non-chemists,” said study co-leader Dr Martin D Burke, an Illinois Professor of chemistry and of the Carle Illinois College of Medicine, as well as a medical doctor. . And we found the needle.”.

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Drug Discovery World

JULY 29, 2022

Australian researchers based may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold. Senior study author and head of Mater Research’s Chronic and Integrated Care Program, Professor Josephine Forbes said the protein discovery was an exciting development.

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Insulin Doctors Doctor Protein 52

The Pharma Data

JANUARY 11, 2021

They give the body a blueprint to create a bit of the virus that causes COVID-19, called a spike protein. Once you are vaccinated, the cell’s machinery uses the blueprint to make the spike protein. This protein then appears on the surface of the cell and the immune system responds to it.

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Drug Discovery World

AUGUST 31, 2022

Amir Abdo Alsharabasy, a CÚRAM doctoral candidate working in the laboratory of Professor Abhay Pandit, is working on the design of nitric oxide scavengers to form a new treatment approach for this aggressive form of breast cancer.

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Hormones Doctors Doctor Clinical Trials 52

The Pharma Data

NOVEMBER 4, 2020

The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. Your doctor will decide if you need additional vaccination. About ULTOMIRIS ®.

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Doctors Doctor Vaccination Vaccine 52

XTalks

JUNE 8, 2021

SMA is caused by mutations in the survival motor neuron 1 ( SMN1) gene, which along with the SMN2 gene, encode the SMN protein. It is administered as a one-time IV administration and expression of the SMN protein from the gene improves muscle movement and function, and ultimately survival. With a price tag of over $2.5

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Gene Therapy Gene Protein Trials 110

The Pharma Data

JUNE 29, 2021

Susan previously led early-stage Oncology R&D, overseeing the successful progression of seven programmes into Phase III trials, with four new medicines now approved in countries around the world. She will join the Company’s Senior Executive Team and report to Chief Executive Officer, Pascal Soriot.

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Development Research Medicine Doctors 52

STAT News

MARCH 6, 2023

Still, when doctors told her last year that the cancer was growing despite two operations, radiation therapy, and a fifth regimen of chemotherapy, the retired business-meeting facilitator decided to do something unorthodox: spend $83,000 out of pocket on an unproven experimental cancer vaccine.

Vaccination 98

Vaccination Vaccine Drugs Clinical Trials 98

Drug Discovery World

JANUARY 22, 2024

For the patient as well as for doctors, this means creating more time to make decisions, as the company believes: “Patients – and their quality of life – shouldn’t have to wait for a broken system to provide an answer six months too late.

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Engineer Immune Response Drugs Vaccination 59

Advarra

MARCH 10, 2023

Red blood cells contain hemoglobin, a protein that carries oxygen. Moss is hopeful a renewed focus on diversity in clinical trials will improve current asset pipelines for SCD cures. Additionally, Moss noted recent headlines have indicated the pipeline of medicines in development for sickle cell disease are shrinking.

Clinical Trials 98

Clinical Trials Clinical Trials Trials Doctors 98

The Pharma Data

MAY 14, 2021

Medical Convention at Baylor College of Medicine, Texas. For example, did you know that, ounce per ounce, spirulina contains twelve times the digestible protein of beef? It’s a far better protein than beef, and it contains a much healthier mineral balance (such as magnesium) that just isn’t found in beef.”

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The Pharma Data

NOVEMBER 22, 2020

SAN DIEGO–( BUSINESS WIRE )– Vividion Therapeutics , a biotechnology company discovering and developing selective small molecule medicines that drug traditionally inaccessible targets, today announced that Jeffrey Hatfield has been appointed as the company’s chief executive officer. 23, 2020 13:30 UTC. About Vividion.

Life Science 52

Life Science Medicine Pharmacy Doctors 52

The Pharma Data

APRIL 29, 2022

SK bioscience and GSK announced submission of a biologics license application for SKYCovione™ a recombinant protein-based COVID-19 vaccine candidate adjuvanted with GSK’s pandemic adjuvant, to the Korean Ministry of Food and Drug Safety (KMFDS) following positive Phase III clinical data.

Vaccination 52

Vaccination Vaccine Clinical Trials Clinical Trials 52

Drug Discovery World

AUGUST 16, 2023

Triple negative cancers are not driven by any of the three molecules that can be blocked by targeted hormone receptor drugs – the HER2 protein and two hormone receptors for oestrogen and progesterone – and so current treatment options are limited.

Genetics 52

Genetics Gene Hormones RNA 52

The Pharma Data

JANUARY 24, 2021

Kevin McVary, director of Loyola Medicine Men’s Health Center, in Maywood, Ill., “Men don’t always focus on their health and, in fact, men are less likely to see a doctor or utilize health resources, and wait longer than women to seek care. It’s important to schedule an appointment with your doctor.

Doctors 52

Doctors Doctor Protein Medicine 52

The Pharma Data

DECEMBER 31, 2020

“We hope these results will help doctors understand the full spectrum of problems patients may suffer so that we can come up with better treatments,” he explained in an NIH news release. 30 in the New England Journal of Medicine. The spots were surrounded by T cells — signs of an immune response. © 2020 HealthDay.

Immune Response 52

Immune Response Containment Doctors Doctor 52

Drug Discovery World

APRIL 3, 2023

DS: What motivated you and Dr David Bunka, CTO, to create Aptamer and did you imagine you would one day be operating on such a global scale?    AT : We initially met at the University of Leeds, where David was a post-doctoral researcher studying aptamers, and I was completing my PhD. Optimer binders are engineered to overcome these problems.

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The Pharma Data

JANUARY 29, 2021

” Just how COVID-19 affects the brain remains unclear, but doctors and researchers increasingly see evidence that wide-ranging neurological problems persist long after the initial infection is gone. One recent study in mice suggests it may be possible for the viral protein to cross the blood-brain barrier.

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Research Protein Medicine Doctors 52

XTalks

JUNE 30, 2023

Hemophilia A is a rare genetic bleeding disorder that is caused by a mutation in the gene that encodes the key blood clotting protein factor VIII (FVIII). Hemophilia A affects approximately one in 10,000 individuals and has a higher incidence than hemophilia B. The disorder primarily affects males.

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The Pharma Data

JUNE 1, 2022

Dr. Anderson earned her doctorate in Biological Sciences at the University of Warwick in the field of microbial ecology and then completed two post-doctoral fellowships. Anderson worked at Merck Research Laboratories where she founded its prokaryotic bio-combinatorial engineering laboratory and initiated a bacterial vaccine program.

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The Pharma Data

DECEMBER 31, 2020

Doctors on the pandemic’s front line say people shouldn’t panic, but should definitely adhere even more closely to proven infection control measures, like mask wearing and social distancing. He’s an emergency medicine physician at Lenox Hill Hospital in New York City. THURSDAY, Dec. and abroad,” said Dr. .

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Vaccination Vaccine Protein Genome 52

XTalks

AUGUST 5, 2020

Xtalks spoke with Dr. Suzanne Schindler, a neurologist at the Washington University School of Medicine in St. p-tau217 is a type of tau protein that forms the primary component of neurofibrillary tangles, which accumulate in the brain to give rise to the condition. In PET scan imaging, compounds that bind to the neuronal proteins (i.e.

Protein 66

Protein Research Development Life Science 66

pharmaphorum

JANUARY 29, 2021

‘Cutting edge’ is, for once, a truly apt description when it comes to gene editing – both because the field is pushing medicine into areas we might never have dreamed possible, and because these technologies involve literally cutting DNA at a specific point in the genome. The genomic medicine journey.

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Gene Editing Gene Gene Therapy In-Vivo 145

pharmaphorum

NOVEMBER 9, 2022

Haemophilia is a rare genetic bleeding disorder, occurring in one in every 5,000 (Haemophilia A) to 30,000 (Haemophilia B) male births, and is associated with an increased bleeding tendency due to a deficiency of blood clotting proteins, called coagulation factors, which are needed for the blood to clot.†. References. Berntorp E.,

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Drug Discovery World

OCTOBER 18, 2023

As such, they offer highly stable expression of human genes, mRNA, and proteins. in Cell Biology and Biochemistry from University College London and was a post-doctoral fellow at Albert Einstein College of Medicine in New York City. She received a Ph.D. References 1: U.S.

Gene Therapy 64

Gene Therapy Gene Clinical Trials Clinical Trials 64

XTalks

FEBRUARY 16, 2023

Quviviq is an FDA-approved prescription medicine that helps treat insomnia in adults, with a low risk of dependence and side effects. Doctors often recommend focusing on improving sleep hygiene first by establishing a regular bedtime, reducing consumption of coffee and other stimulants and limiting screen time before bed.

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The Pharma Data

JANUARY 17, 2021

The medicine, an anti-SARS-CoV-2 immunoglobulin, given subcutaneously, would provide immediate protection after exposure to the virus and could be used to protect the elderly and healthcare workers. . It develops this plasma into essential medicines used to treat chronic, rare and, at times, life-threatening conditions.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Containment 52

Drug Discovery World

JULY 29, 2022

Isselbacher Professor of Medicine in the Field of Gastroenterology at Harvard Medical School and Massachusetts General Hospital, a core institute member at the Broad Institute of MIT and Harvard, and co-director of the Center for Microbiome Informatics and Therapeutics at MIT. muciniphila’s cell membrane. That discovery was quite surprising.

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Bacterium Research Bacteria Immune Response 52

Pharmaceutical Technology

OCTOBER 5, 2022

Technology is advancing the possibilities of healthcare treatments, from the development of innovative new drugs to freeing up time for doctors thanks to monitoring devices for patients with conditions such as diabetes and high blood pressure. The startup is based at Edinburgh Royal Infirmary Campus in the Centre for Regenerative Medicine.

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The Pharma Data

JULY 21, 2021

About VENCLEXTA® (venetoclax) VENCLEXTA ® /VENCLYXTO ® (venetoclax) is a first-in-class medicine that selectively binds and inhibits the B-cell lymphoma-2 (BCL-2) protein. VENCLXEXTA/VENCLYXTO targets the BCL-2 protein and works to help restore the process of apoptosis. Call your doctor for medical advice about side effects.

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Medicine Vaccination Vaccine Clinical Trials 52