STAT News

MARCH 10, 2023

 Two recent studies aimed to quantify how much R&D costs impact a drug’s price, and how much effectiveness correlates with its price — factors that might, in theory, help justify a sizable price tag. But neither factor has much effect, the studies concluded.

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Pharmaceutical Technology

DECEMBER 5, 2022

Collectively, cannabinoid receptors (CB1 and CB2) are currently the most popular targets in preclinical stage of development, with 391 drugs tagged in total. Strict policies in Asia, the Middle East and Africa could lead to restricted progress in late-stage development, which could impact the future market.

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Rethinking Clinical Trials

JANUARY 31, 2024

The Health AI Partnership held a workshop that examined how to assess the potential future impact of a new AI solution on health inequities. The final key decision point is lifecycle management, which includes monitoring and maintaining the AI product and updating or decommissioning the product.

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Pharmaceutical Technology

MAY 1, 2023

CTH-004 is developed by genetically altering patient T cells for inserting a chimeric antigen receptor (CAR) to target a marker (TAG-72) on ovarian cancer cells and delete genes which are involved in T cell function suppression. Shunxi will also hold an option to negotiate rights to other CAR-T products, which include the licenced IP.

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Rethinking Clinical Trials

NOVEMBER 1, 2022

Important issues early on included COVID-19’s effects on the workplace, vaccine access and willingness, and impact on home life. The HERO Registry explored topics that mattered most to participants and found these topics changed with time. Later, burnout and lack of appreciation and support became larger issues. pctGR, @Collaboratory1.

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The Pharma Data

FEBRUARY 22, 2022

As part of its on-going work to track variants, WHO’s Technical Advisory Group on SARS-CoV-2 Virus Evolution ( TAG-VE ) met yesterday to discuss the latest evidence on the Omicron variant of concern, including its sublineages BA.1 Reinfection with BA.2 2 following infection with BA.1 WHO will continue to closely monitor the BA.2

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Rethinking Clinical Trials

SEPTEMBER 30, 2022

The trial was part of a “Pay for Success” contract that enabled the state to promise funds for further expansion conditional on positive evidence of impact from the randomized trial. The primary evaluation question for the trial was what is the impact of NFP on health outcomes when delivered at scale? Discussion Themes.

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The Pharma Data

NOVEMBER 29, 2021

1.1.529 a variant of concern, named Omicron, on the advice of WHO’s Technical Advisory Group on Virus Evolution (TAG-VE). Effectiveness of vaccines : WHO is working with technical partners to understand the potential impact of this variant on our existing countermeasures, including vaccines. Recommended actions for countries.

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Rethinking Clinical Trials

MARCH 15, 2023

A cluster-average treatment effect better enables the evaluation of an intervention or treatment’s impact directly on clusters. Participant-average treatment effect will demonstrate the population-effect when going from one intervention to another.

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Rethinking Clinical Trials

OCTOBER 13, 2022

The HandiCAP trial asked the question do intraoperative handovers of anesthesia care have an impact on patient outcomes? The post Grand Rounds October 7, 2022: Impact Of Handovers Of Anesthesia Care On Morbidity And Mortality (Melanie Meersch-Dini, MD) appeared first on Rethinking Clinical Trials. pctGR, @Collaboratory1.

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Rethinking Clinical Trials

FEBRUARY 16, 2023

Discussion Themes – How did the various types of notifications in the ICD-Pieces study impact opt-outs? Tags #pctGR, @Collaboratory1 The post Grand Rounds Ethics and Regulatory Series February 10, 2023: Informing and Consenting: What Are the Goals? (P. What should they agree (not object) to? The opt-outs were also very different.

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Rethinking Clinical Trials

JUNE 7, 2023

The pragmatic elements were already in place so when COVID happened the main thing that had the biggest impact on our study was the shortage of study coordinators that effected every trial, and a few of our study sites went under due to difficulty of staffing and sustaining a research enterprise.

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World of DTC Marketing

SEPTEMBER 7, 2022

In pharma, growth depends on new products with hefty price tags when over 80% of voters want lower costs for their prescription drugs. COVID-19 has not impacted the number of launches in the oncology space, as 2020 and 2021 have seen similar rates of drug launches as in 2019. ” The U.S.

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Rethinking Clinical Trials

JANUARY 17, 2024

Tags #pctGR, @Collaboratory1 The post Grand Rounds January 12, 2024: Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce Covid-19 Resources (Erin K. The COVID Therapeutics Committee worked with the state health department to develop a policy for fair allocation of scarce medications to treat COVID-19.

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Pharmaceutical Technology

JUNE 29, 2022

For example, while orphan drug designations have more than doubled in the last decade compared to the previous one, only 16% of therapies with orphan tags have managed to gain FDA approval in some indications.

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Rethinking Clinical Trials

JULY 19, 2023

The objective of COORDINATE-Diabetes trial was to improve the implementation and adoption of these therapies by testing the impact of a clinic-level, multifaceted intervention on the prescription of 3 key groups of evidence-based therapies. However, these therapies are highly underused in routine clinical practice. Granger, MD; Neha J.

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Rethinking Clinical Trials

JULY 14, 2023

The study found that virtual parenting support coincided with the COVID-19 and helped families deal with the impact of the pandemic; GGC was delivered with high fidelity across cohorts, sessions, and sites; parents were satisfied with virtual GGC, with parents valuing the flexibility, connection and community.

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Rethinking Clinical Trials

AUGUST 18, 2022

The Trial Innovation Network Recruitment Innovation Center aims to positively impact human health by improving participant enrollment and retention in multi-center clinical trials. When you live in an environment where you have been minoritized and are experiencing discrimination, it has an impact on your biology. New Ideas study.

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Pharmaceutical Technology

MAY 15, 2023

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

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Pharmaceutical Technology

APRIL 13, 2023

Although the findings in the report are only preliminary, they shed light at the considerations behind the high price tags of gene therapies. Sickle cell disease is an inherited blood disorder that is caused by mutations in the HBB gene, which codes for the oxygen-carrying protein haemoglobin in red blood cells.

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XTalks

MAY 1, 2024

The Impact of Inflation on Grocery Shopping According to Statista , the food inflation rate in the US reached approximately 5.8 With its expansive range and competitive pricing, bettergoods is poised to become a key player in the grocery sector, inviting customers to enjoy premium products without the premium price tag.

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Drug Discovery World

NOVEMBER 28, 2023

This is likely to have a positive impact on dopaminergic neurons undergoing chronic degenerative processes, which result in functional impairment. Importance of healthy mitochondrial function Dysfunctional mitochondria are usually tagged for removal via mitophagy with a protein ‘flag’ called ubiquitin.

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Rethinking Clinical Trials

MAY 10, 2023

All of Us will expand the data available for participants, launch ancillary studies as a core and scalable capability, establish a diverse global community of 10,000 researchers, and incorporate participant return of value into data collections and assess its impact. We want to make sure that we are not an off ramp for clinical trials.

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Drug Discovery World

JANUARY 9, 2023

The engineered tumour cells were also designed to express factors that would make it easy for the immune system to spot, tag, and remember them, priming the immune system for a long-term antitumour response. . This dual-action cell therapy was safe, applicable, and efficacious in these models. .

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Rethinking Clinical Trials

AUGUST 30, 2023

There were also challenges with many software and security updates that impacted to the dashboard. Tags #pctGR, @Collaboratory1 The post Grand Rounds August 25, 2023: Pragmatic Trial of an EHR Application to Display Real-time PRO Data: Successes and Challenges (Gabriela Schmajuk, MD, MS) appeared first on Rethinking Clinical Trials.

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XTalks

DECEMBER 13, 2023

In a press release , bluebird bio CEO Andrew Obenshain said, “Lyfgenia has the potential to have a transformational impact for patients who currently live under the shadow of unpredictable and debilitating vaso-occlusive events. Vertex-CRISPR’s Casgevy has a US list price of $2.2 million and bluebird’s Lyfgenia is 40 percent higher at $3.1

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Rethinking Clinical Trials

NOVEMBER 21, 2023

Lessons learned: The text message intervention improved medication refill adherence, the effectiveness was consistent regardless of the type of message delivered, and the differential impact of the intervention across some patient groups. The opt out approach is feasible and drop out rate was lower than expected.

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Rethinking Clinical Trials

OCTOBER 11, 2023

This was an impactful collaboration between NIH investigators and study teams and methodologists. Tags #pctGR, @Collaboratory1 The post Grand Rounds October 6, 2023: Hybrid Studies Should Not Sacrifice Rigorous Methods (David M. The real interest is in finding out about how to improve acceptability, adoption, fidelity, etc.

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World of DTC Marketing

JUNE 23, 2021

Alzheimer’s really is a devastating diagnosis, and if Biogen had actually produced a game-changing product to slow its worst symptoms, it would have an immeasurable impact on millions of lives. Not to mention the $56,000 annual price tag. That might be tolerable if the drug actually worked.

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pharmaphorum

JANUARY 11, 2022

He is the principal investigator for a clinical study that will evaluate the impact of BNT200 on quality of life, mood, and symptoms of patients diagnosed with AML. The post Blue Note leukaemia DTx gets FDA breakthrough tag appeared first on. Other DTxs are aimed at people being treated for breast and lung cancers.

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XTalks

OCTOBER 19, 2023

So, what makes this sauce brand worth billions of dollars and will Campbell’s new ownership impact the brand? Despite the premium price tag, the brand has gained a cult following thanks to its inclusion of high quality ingredients and successful word-of-mouth marketing.

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pharmaphorum

AUGUST 17, 2020

In this article Joanna Carlish, managing director of financial services at Tag Americas , and Robb DeFilippis, Tag Americas’ managing director, life sciences, go head-to-head to discuss marketing within a regulated industry. Joanna Carlish, managing director, financial services, Tag Americas. Virtual connections.

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XTalks

MAY 2, 2024

AI helps us pinpoint the pain points of our clients and solve them more efficiently,” she mentioned, underscoring the technology’s impact on enhancing operational efficiency. Sam Davidson, Director of Food Safety at The Acheson Group (TAG) , also emphasized the need for fundamental training for frontline workers in the food industry.

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Rethinking Clinical Trials

OCTOBER 27, 2022

If we eliminate all the states where reproductive rights data could be harmful, is that going to impact site selection? -How can we do research in states that are restricting access to reproductive health and keep patients safe? We don’t want to create a disparity like that and have these women lose access to research. pctGR, @Collaboratory1.

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XTalks

NOVEMBER 3, 2022

Michael Mason, EVP and president of Lilly Diabetes said Lilly is “taking actions to maximize production supply for our current facilities while we ramp up our new manufacturing facilities,” and will “work hard to avoid or minimize any short-term impact for people living with Type 2 diabetes,” as it builds up its supply chain capacity.

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Intouch Solutions

APRIL 11, 2024

Pre-Clinical : Deeper comprehension of the impacts and outcomes associated with a particular drug. The Medical Information Chatbot (HCP virtual assistant) is one of the tools that has been most impacted by the advent of GPT AIs. Clinical : Optimized efficiency, inventory management, and service quality of clinical trials.

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pharmaphorum

DECEMBER 12, 2022

She told ASH that current therapies for ITP have limitations, including tolerability issues, lacklustre efficacy and a short duration of effect, as well as having a limited impact on quality of life.

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