Scienmag

MAY 18, 2021

Scientists link genetic makeup of bacteria in the human gut to several human diseases We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome.

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The Pharma Data

JUNE 14, 2023

Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. aeruginosa infections.

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Scienmag

MARCH 2, 2021

— Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals. Process paves a road to safe, ethical, and fast drug manufacturing Credit: Rensselaer Polytechnic Institute TROY, N.Y.

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STAT News

NOVEMBER 14, 2022

In this video, we chat with health policy and drug pricing researcher Hussain Lalani; Julia Joung, a molecular biologist developing genetic screening technologies; and Avinash Manjula Basavanna, who researches engineered living materials and has developed a printable ink made from bacteria.

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Scienmag

APRIL 6, 2021

A Berkeley Lab-led team is digging into the bizarre bacteria-produced nanomachines that could fast-track microbiome science Credit: Antara Mutalik Imagine there are arrows that are lethal when fired on your enemies yet harmless if they fall on your friends.

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pharmaphorum

OCTOBER 7, 2020

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery. What started as a curiosity?driven,

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Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. The Rockefeller University 2 recently reported the development of a synthetic antibiotic that could potentially work against drug-resistant bacteria.

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Scienmag

JANUARY 12, 2021

Martins Scientists have used gene-editing advances to achieve a tenfold increase in the production of super-bug targeting formicamycin antibiotics. The John Innes Centre researchers used the technology to create a new strain of Streptomyces formicae bacteria which over-produces the medically promising molecules. Credit: Dr Dino J.

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Scienmag

MARCH 9, 2021

Modern hospitals and antibiotic treatment alone did not create all the antibiotic resistant strains of bacteria we see today. By using analytical and sequencing technology that has only been developed in recent years, scientists from Wellcome […].

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The Pharma Data

JULY 11, 2021

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. The immune system is mentioned particularly frequently.

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STAT News

SEPTEMBER 30, 2022

The shortlist includes researchers who elucidated how cells make energy, those who discovered the chemical chatter of bacteria, many of the brilliant minds who shepherded us into the “ era of the genome ,” and most prominently, the pioneers behind the mRNA Covid vaccines. Read the rest…

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The Pharma Data

JANUARY 4, 2021

But scientists at the University of California (UC), Santa Barbara, believe fluoride may offer hope in the fight against antibiotic-resistant bacteria. The UC Santa Barbara research uses a method that addresses not only antibiotic overuse, but also the containment of genetically modified organisms (GMOs). “If

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The Pharma Data

DECEMBER 30, 2020

Our digestive tract is home to trillions of bacteria as well as fungi and viruses – these are known as the gut microbiome. Scientists now know that this microbiome is critical to our overall well-being. Some call it our second brain. Say yes to a little dirt.

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XTalks

JANUARY 6, 2021

Related: Scientists Use Llama Antibodies to Neutralize COVID-19. Owing to their size, they can be grown in bacteria as opposed to larger animal or human cells, making them easier and cheaper to produce. These regions play a crucial role in the detection of antigens on viruses, bacteria and other pathogens.

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Drug Discovery World

DECEMBER 14, 2023

In addition, Glasgow is an attractive location to the brightest and best scientists from all over the world.  Its researchers represent some of the best scientists from around the world who have come together to work towards better outcomes for patients today and in the future.”

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Drug Discovery World

FEBRUARY 6, 2024

million data points from ALS patient tissue and genetics datasets to discover loss of endolysosomal function as a new causative mechanism in ALS, and uncovered PIKfyve as a promising new therapeutic target. In June 2023, lab automation company Opentrons launched its Flex robots for scientists using generative AI. Obulytix is not alone.

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XTalks

NOVEMBER 3, 2023

CRISPR works as genetic scissors to edit parts of the genome. The CRISPR-Cas9 gene editing system was first discovered to be endogenous in bacteria. The FDA scientists agreed that Vertex’s clinical trial results, made available in documents published last week, were “strongly positive.”

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The Pharma Data

MAY 22, 2023

Pathogen genomics analyzes the genetic code of viruses, bacteria and other disease-causing organisms to understand how infectious they are, how deadly they are, and how they spread.

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Drug Discovery World

MARCH 14, 2023

For the first time, researchers have developed an mRNA vaccine that is 100% effective against a type of bacteria that is lethal to humans, paving the way for effective vaccination against antibiotic-resistant bacteria. However, until now scientists believed that mRNA vaccines against bacteria were biologically undoable.

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XTalks

FEBRUARY 11, 2021

This has ushered in a new era of genomics that is fostering rapid, detailed and personalized insights into human genetics. Xtalks is celebrating the International Day of Women and Girls in Science with a special overview of notable female scientists who have made revolutionary contributions to the field of genetics.

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The Pharma Data

MARCH 13, 2022

assistant professor of medicine at the Johns Hopkins University School of Medicine and staff scientist at NIAID. CD8+ T cells are nicknamed killer T cells (they’re also known as cytotoxic T cells) for their ability to eliminate foreign invaders such as bacteria and viruses from the body. population.

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Roots Analysis

OCTOBER 19, 2023

Bacteria plays a crucial role in maintaining the ecosystem balance. However, there are few species of bacteria that can cause several infectious diseases ( such as strep throat, salmonellosis, tuberculosis, whooping cough ). The overuse of antibiotics has resulted in the emergence of multi-drug-resistant bacteria. coli and P.

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The Pharma Data

FEBRUARY 22, 2021

Born in 1970, the British and American research scientist has been Director of the Department of Microbiome Research at the Max Planck Institute for Developmental Biology in Tübingen since 2016. Before, she was associate professor at Cornell University in the Department of Molecular Biology and Genetics.

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STAT News

SEPTEMBER 30, 2022

For a while, scientists thought the trillions of microbes on our bodies lived in landscapes connected to the outside world — our skin, hair, and gut — but research in the last few years has shown that’s not so. Read the rest…

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XTalks

DECEMBER 14, 2022

It’s a new genetic way of potentially targeting these really hard to treat diseases,” said Abudayyeh, a McGovern Fellow at MIT’s McGovern Institute for Brain Research, in MIT’s press release. Integrases are used by viruses called bacteriophages to insert their genetic material into bacteria. percent of these cells.

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Drug Discovery World

APRIL 30, 2024

Messenger RNA (mRNA) has come into focus within the drug discovery and development as an exciting tool to deliver genetic information. Their functions such as carrying oxygen, providing structural support to cells, transmitting biological processes to cells, and fighting viruses and bacteria, are essential to human health.

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Drug Discovery World

AUGUST 10, 2022

The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. Cells from solid tumours are genetically heterogeneous both between and within tumours, making it challenging to identify a single, selective antigen target for treatment.

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pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. While it is a very rare form of epilepsy, it is such a cheap and harmless medication that it is often used as a first-line therapy for infants in intensive care who have no genetic diagnosis.

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Drug Discovery World

JULY 18, 2023

Incorporating in vivo pooled CRISPR screens has allowed for the interrogation of thousands of genetic perturbations in cells, leading to the determination of the involvement of molecules (PTPN2, ADAR1, or DHX37) in immune checkpoint inhibitor (ICI) responsiveness and T cell activation.

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Drug Discovery World

FEBRUARY 15, 2023

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Genetically modified T cells stimulated with IL2 are now administered as cell therapy for multiple cancer cell types with beneficial results 3,4. EMBO Mol Med 2017;9:137–53.doi:10.15252/emmm.201606857pmid:[link]

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The Pharma Data

JANUARY 21, 2021

They are now working to identify what genetic aberrations are causing ALS in about half of the Maltese patients. Scientists at KU Leuven have identified a biological mechanism behind irritable bowel syndrome (IBS) and other food intolerances. How the Immune System Drives Brain Aging. The research was conducted in mice and humans.

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The Pharma Data

MAY 15, 2021

The scientific study of how to undo genetic illnesses – like HCT – is called epigenetics. So identical twins can have identical genes – yet different genetic illnesses. Now that scientists know what causes HCT we finally have the power to directly influence those causes. And that’s exactly what I learned to do.

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XTalks

DECEMBER 24, 2020

However, for virologists like Lori Frappier, PhD, professor in the department of molecular genetics at the University of Toronto, the outbreak of SARS-CoV-2 was less of a surprise and more of an inevitability. The female scientist duo became the first women to be jointly awarded a Nobel Prize, making it a winning moment for women in science.

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