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HPAPIs – Current Interest of the Pharmaceutical Industry

Roots Analysis

This has led to their widespread production and extensive use in the treatment of various indications including hormonal imbalances, oncological disorders and respiratory disorders. Hormones: Biologic HPAPIs which are not classified as oncology drugs include hormones, narcotics and retinoids.

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Skincare Routines for People with Hidradenitis Suppurativa

Olympian Clinical Research

While the exact cause is unknown, factors like genetics, inflammation, and hormones play a role. Here are some common triggers of HS: Hormonal Changes: Many individuals with HS report flare-ups during periods of hormonal change, such as menstruation, pregnancy, or menopause.

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Inviting Healthy Men to Help Find a New Potential Treatment for Achondroplasia (ACH)

Trialfacts

Achondroplasia (ACH) is a genetic condition that affects children’s growth. CNP is a hormone produced by the body that plays an important role in the bone growth of children. Must be willing to abstain or limit the use of nicotine-containing products to no more than 5 cigarettes/week until the end of the study.

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Immunotherapies could target aggressive pancreatic cancer, research indicates

The Pharma Data

The research, published in the journal Gut, revealed that 83% of aggressive, metastatic-like tumours contained particularly high levels of a gene called TLR3, part of a damage-alert system that mimics the infection response triggered by viruses, drawing immune cells to the tumour.

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The regulatory round-up: Eight key FDA decisions

Drug Discovery World

Read more: FDA Fast Track Designation for retinitis pigmentosa treatment Drug candidate for TUBB4a leukodystrophy, SynaptixBio The FDA has granted Rare Paediatric Disease (RPD) Designation to SynaptixBio’s drug candidate for TUBB4a leukodystrophy – a genetic and debilitating condition which mainly affects babies and young children.

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J&J’s Akeega Approved as First Combo Treatment for BRCA-Positive Prostate Cancer

XTalks

Akeega is a dual-action tablet (DAT) that contains the company’s androgen receptor-targeting hormone therapy Zytiga (abiraterone acetate) and PARP inhibitor (poly [ADP-ribose] polymerase inhibitor) niraparib. Niraparib is also sold by GSK under the name Zejula in other indications.

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Type 1 Diabetes Vaccine: Does Diamyd Have a Winning Formula?

XTalks

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. Specifically, the vaccine contains human recombinant glutamate decarboxylase 65 (GAD65) protein conjugated to aluminum hydroxide (GAD-alum).