pharmaphorum

NOVEMBER 23, 2021

Genomics England, the Department of Health and Social Care’s genome-sequencing hub, has this year announced that support for whole genome sequencing (WGS) has reached a level at which its national rollout on the NHS may someday become a reality. Only when genomic databases are diverse can we ensure that we all benefit equally.

Genome 115

Genome Genomics Genetics Doctors 115

Scienmag

JANUARY 27, 2021

Credit: John Wallace, VCU Massey Cancer Center Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

DNA 52

DNA Genome Genomics Doctors 52

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate.

Genome 87

Genome Genomics Genetics Genome Project 87

pharmaphorum

FEBRUARY 25, 2021

Chaired by the Genetic Alliance, the virtual meeting saw representatives from Scotland, England, Wales, and Northern Ireland discuss the implementation of the UK Government’s Rare Disease Framework. We now know that 80% of rare diseases have a genetic origin. Genomic technology, therefore, has a key role to play in our work,” he said.

Genome 95

Genome Genomics Genetics Medicine 95

Drug Discovery World

JUNE 5, 2023

Meet the biotech: Enhanc3D Genomics Enhanc3D Genomics was spun out from the laboratories of Dr Stefan Schoenfelder and Professor Peter Fraser, who pioneered research into the dynamic spatial organisation of the genome at the Babraham Institute in Cambridge, UK.

Genome 52

Genome Genomics Life Science Genetics 52

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate.

Genome 74

Genome Genomics Genetics Genome Project 74

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. ZFPs can be engineered to make zinc finger nucleases, or ZFNs, which are proteins that can be used to edit genomes by knocking select genes in or out to specifically modify DNA sequences.

Gene Editing 144

Gene Editing Gene Gene Therapy In-Vivo 144

pharmaphorum

DECEMBER 21, 2021

In a recent webinar held by pharmaphorum, in partnership with IQVIA, a discussion was held looking at how to make academic and commercial medical research more efficient, while also looking at the opportunity of genomic data to bring benefits to patients and healthcare systems. The potential to leverage genomic data.

Development 97

Development Genome Genomics Drugs 97

pharmaphorum

AUGUST 11, 2022

There have been great strides made in genomics to refine tools that determine the safest, most effective course of treatments for patients across a number of disease states. The participants undergo monitoring for genetic variations that could potentially negatively impact their reaction to therapies. About the Author.

Genome 95

Genome Genomics Genetics Drugs 95

The Pharma Data

AUGUST 16, 2021

The antiviral agent incorporates RNA-like building blocks into the RNA genome of the virus. If this genetic material is further replicated, defective RNA copies are produced and the pathogen can no longer spread. ” Mutations in the genome stop the virus. Molnupiravir is currently being tested in clinical trials. .”

RNA 52

RNA Drugs Genome Genomics 52

Drug Discovery World

NOVEMBER 27, 2023

Predictable milestones and future perspectives Transposons (genetic elements) have been used to deliver a gene of interest into transcriptionally active sites of the cell line genome leading to rapid cell line development eventually resulting in high titers of the recombinant protein drug.

Production 59

Production Engineer Gene Editing Gene 59

pharmaphorum

SEPTEMBER 12, 2022

Across LabCorp , we innovate through science and technology, with access to approximately 2,500 [doctors] and PhDs and over 700 patients. Everyone’s genetic makeup differs, and each person’s cancer experience is unique to them – how cancer develops, how fast it spreads, which drugs it responds to, and more. Tailored oncology.

Genome 105

Genome Genomics Clinical Trials Clinical Trials 105

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Genuity Science focuses on population genomics as a tool to derive novel biological insights through partnerships with industry-leading pharmaceutical and biotech companies.

Research 98

Research Biobanking Drugs Genome 98

Bioengineer

JULY 22, 2021

Geneticists from Trinity College Dublin have discovered how a specific genetic mutation called H3K27M causes a devastating, incurable childhood cancer, known as diffuse midline glioma (DMG), and – in lab studies working with model cell types – successfully reverse its effects to slow cancer cell growth with a targeted drug.

Genetics 52

Genetics Drugs Clinical Trials Clinical Trials 52

pharmaphorum

NOVEMBER 3, 2020

Allison’s son David was just six when he started displaying the symptoms of (R)20, a genetic condition that can cause multiple, uncontrollable seizures, declines in cognition and mobility, and terrifying hallucinations. There are no clinical practice guidelines, meaning doctors treat on a case-by-case basis.

Gene Sequencing 113

Gene Sequencing Gene Genome Genomics 113

The Pharma Data

DECEMBER 17, 2020

Dr. Lisa Forbes — his doctor and co-author of a letter describing his case in the Oct. This patient had a genetic mutation that ruxolitinib is known to work on. Forbes said it’s not clear if other people with type 1 diabetes also have this specific genetic mutation. WEDNESDAY, Oct.

Insulin 52

Insulin Genetics Doctors Doctor 52

pharmaphorum

MARCH 19, 2021

Approximately 85% of rare diseases are genetic, offering significant opportunities to develop better treatments as our understanding of the human genome improves 1. However, often rare disease patients are ignored by doctors, researchers, and the general public. Referral triggers may also be different.

Branding 52

Branding Genome Genomics Genetics 52

XTalks

MAY 20, 2022

Doctors and physicians rely on the results provided by a clinical scientist to make an accurate prognosis, diagnosis and assessment for a patient’s treatment plan. Interpret medical tests and confer with doctors and physicians for a suitable prognosis and treatment plan. Genetic Science. Clinical Pharmaceutical Science.

Scientist 105

Scientist Life Science Clinical Research Doctors 105

pharmaphorum

OCTOBER 6, 2022

By reducing the disease to its key components, a computer-readable network of disease markers was characterised using genetic, biomarker, and clinical data; the model was also populated with ‘disease vs control’ data. He served as Director of the Lowe Family Genomics Core at the Johns Hopkins University from 2005-15.

In-Vivo 98

In-Vivo Research Genetics Drugs 98

XTalks

OCTOBER 15, 2021

This included segregated wards at Johns Hopkins containing Black patients with cervical cancer whom white doctors would collect samples from without their knowledge or consent. The Lacks family is also concerned over the wide availability of Lacks’ genetic material, saying that “some of the most private information about Ms.

Vaccination 105

Vaccination Vaccine Gene Mapping Doctors 105

The Pharma Data

SEPTEMBER 1, 2021

Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. The researchers used CRISPR-Cas9 genome editing technology to make cells that secrete a biologic drug in response to inflammation. million adults in the United States. 1 in the journal Science Advances.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

Pharmaceutical Technology

NOVEMBER 4, 2022

And we're building this Data Commons, bringing in imaging data, genomic data, clinical health record data, which in Scotland is really well annotated already,” says McNeil. All data is anonymised to protect patient confidentiality. We're trying to understand why it’s increasing so much across the world, but Scotland in particular.

Medicine 130

Medicine Development Research Gene 130

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

Genetics 52

Genetics Research Medicine Clinical Research 52

pharmaphorum

FEBRUARY 26, 2021

Every time a patient with a rare condition walks into a hospital, doctors face the probable challenge of starting from scratch. Genetic testing has played a big role in enhancing the diagnosis process. For instance, the UK government’s 100K Genomes Project has achieved its goal of sequencing the genomes of 100,000 people in 2019.

Drugs 59

Drugs Genome Project Genome Genomics 59

Delveinsight

AUGUST 11, 2021

Many tech related tools are being developed to create applications or devices with higher accuracy using technology like genetics and pathology. Virtual and Augmented Reality Programs are aiding doctors by making patients see a complete technique of how a surgery is performed. Genome Sequencing. Drug Development.

Medicine 90

Medicine Drug Delivery Development Drug Delivery Systems 90

XTalks

OCTOBER 19, 2023

This specialization can often be achieved during graduate research, post-doctoral work or industry-specific training programs. Additionally, advances in technologies in fields like genomics, proteomics and cell biology necessitate specialized assays. Interning provides industry-relevant experience and can also help with networking.

Scientist 59

Scientist Development Research Compliance 59

Roots Analysis

SEPTEMBER 1, 2023

Blue Ocean Strategy Example: Foundation Medicine has developed a genomic profiling test that helps oncologists identify the best treatment options for their patients based on their genetic makeup. As the field continues to advance, it is expected to have a profound impact on the future of medicine.

Drug Delivery 52

Drug Delivery Marketing Drug Delivery Systems Drugs 52

XTalks

FEBRUARY 26, 2021

Hollmann was a doctor at the Kalihi Hospital in Hawaii who wanted to find a way to extract the active ingredients of chaulmoogra oil so that it could be effectively administered to patients. He even became known as the “the plant doctor” among local farmers as he had the ability to improve the health of their fields, orchards and gardens.

Scientist 69

Scientist Research Genetics Cosmetics 69

pharmaphorum

SEPTEMBER 13, 2022

Thanks to the dedicated efforts of doctors, patients, carers, and healthcare professionals, people diagnosed with blood cancer are now living longer, with a steady stream of more effective treatments entering the market each year. 2012 – The 100,000 Genomics Project begins. This was an entirely new approach to DNA research.

Genome Project 96

Genome Project Genome Genomics DNA 96

Drug Discovery World

APRIL 21, 2023

SLAS Student Poster Award The SLAS Student Poster Award recognises innovative research by students, graduate students, post- doctoral associates and junior faculty (less than four years in first academic appointment) who are chosen to present a poster during SLAS Europe 2023. It will be led by Björn C.

Doctors 52

Doctors Doctor Genetics In-Vitro 52

pharmaphorum

SEPTEMBER 1, 2020

Another military man in the drugs business was Edward Robinson Squibb, who as a naval doctor during the Mexican-American war of 1846–1848 threw the drugs he was supplied with overboard due to their low quality. This knowledge of genetics and the underlying cause of many diseases, including cancer, has resulted in powerful new drugs.

Medicine 145

Medicine Insulin Pharmacy Drugs 145

pharmaphorum

DECEMBER 7, 2021

They used computational techniques to sift through genetic and other biologic data as well as insurance claims information from a database of more than 7 million patients, and found that sildenafil had the greatest potential as an Alzheimer’s drug.

Drugs 52

Drugs Clinical Trials Clinical Trials Scientist 52

Pharma Marketing Network

JANUARY 20, 2021

In other areas of the industry (such as cell and genetic medicine development) progress continued at an impressively brisk pace despite the pandemic. Douglas Lee of Bayer Pharmaceuticals described this change as a major shift in how patients access healthcare and “a change in the mindset that you need to see the doctor for everything.”

Vaccination 52

Vaccination Vaccine In-Vivo Genetics 52

Pharmaceutical Technology

FEBRUARY 28, 2023

The vast majority of rare diseases have a genetic cause, with well-known examples including cystic fibrosis, sickle cell disease, Huntingdon’s, and various muscular atrophies and dystrophies. This often puts patients in difficult situations where they are passed between doctors until a correct diagnosis is reached.

Marketing 130

Marketing Medicine Production Drugs 130