Drug Discovery World

MARCH 18, 2024

Landmark genetic research could allow doctors to accurately predict whether a patient is at risk of developing common diseases, decades before any symptoms would become evident. He’s going to accelerate personalised medicine based on an individual’s genome.

Genetics 52

Genetics Research Genome Genomics 52

Scienmag

JANUARY 27, 2021

Credit: John Wallace, VCU Massey Cancer Center Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

DNA 52

DNA Genome Genomics Doctors 52

pharmaphorum

MARCH 19, 2021

As data and digital technology become vital to every aspect of life sciences, the industry is increasingly looking beyond biologists, chemists, and doctors to drive its drug development – and finding that technology has a chief role to play in the future of medicine. on Big data: astronomical or genomical? ,

Bioinformatics 57

Bioinformatics Drugs Genome Genomics 57

pharmaphorum

DECEMBER 20, 2022

For example, AI-enabled imaging techniques can help doctors detect diseases earlier and more accurately. Genomic profiling has made it possible to diagnose and treat patients with far greater precision. The pandemic has fuelled these efforts by demonstrating the importance of robust data infrastructure.

Genome 104

Genome Genomics Trials Doctors 104

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome 101

Genome Genomics Genetics Genome Project 101

pharmaphorum

DECEMBER 21, 2021

In a recent webinar held by pharmaphorum, in partnership with IQVIA, a discussion was held looking at how to make academic and commercial medical research more efficient, while also looking at the opportunity of genomic data to bring benefits to patients and healthcare systems. The potential to leverage genomic data.

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Development Genome Genomics Drugs 98

Drug Discovery World

JUNE 5, 2023

Meet the biotech: Enhanc3D Genomics Enhanc3D Genomics was spun out from the laboratories of Dr Stefan Schoenfelder and Professor Peter Fraser, who pioneered research into the dynamic spatial organisation of the genome at the Babraham Institute in Cambridge, UK.

Genome 52

Genome Genomics Life Science Genetics 52

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. ZFPs can be engineered to make zinc finger nucleases, or ZFNs, which are proteins that can be used to edit genomes by knocking select genes in or out to specifically modify DNA sequences.

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Gene Editing Gene Gene Therapy In-Vivo 145

pharmaphorum

SEPTEMBER 14, 2022

. “To solve these, the Voice as a Biomarker of Health project is creating a large, high-quality, multi-institutional and diverse voice database that is linked to identity-protected/unidentifiable biomarkers from other data, such as demographics, medical imaging, and genomics,” they add. ” It will be backed by $3.8

Genome 104

Genome Genomics Doctors Doctor 104

XTalks

APRIL 21, 2023

The application of whole genome sequencing (WGS) to derive a more complete understanding of cancer has been a central goal of cancer researchers even before the first human genome was decoded in 2003. Ultima Genomics has already partnered with other leading biotech startups.

Genome 97

Genome Genomics Bioinformatics Genetics 97

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome 79

Genome Genomics Genetics Genome Project 79

pharmaphorum

FEBRUARY 25, 2021

The Scottish Government has supported the transition of genomic testing for inherited rare disease from the research setting into routine care,” she went on. “As On genomics, he added, the country is going “further and faster”, and ensuring synergy between the Rare Disease Framework and the UK Genomic Healthcare Strategy.

Genome 109

Genome Genomics Genetics Medicine 109

Drug Discovery World

OCTOBER 3, 2022

She has extensive R&D and commercial experience in automated liquid handling and high throughput analytical techniques, spanning both genomics and drug discovery applications. She has played a key role in the launch of the new 3- and 6- head dragonfly discovery. Hammerstein graduated from the University of Oxford with a M.Chem.

Genome 97

Genome Genomics Drugs Engineer 97

pharmaphorum

SEPTEMBER 12, 2022

Across LabCorp , we innovate through science and technology, with access to approximately 2,500 [doctors] and PhDs and over 700 patients. The test informs HCPs through a comprehensive genomic and immune profiling test clinically and analytically validated for all solid tumours. Tailored oncology.

Genome 104

Genome Genomics Clinical Trials Clinical Trials 104

pharmaphorum

APRIL 8, 2022

She collaborated in projects like BIDA-SE (“Possible Uses and Clinical Benefits of Big Data Applications for Rare Diseases”), CORD-MI (“Collaboration for Rare Diseases”) and SATURN (“Smart Doctor Portal for Patients with Unclear Diagnosis”).

Genome 78

Genome Genomics Research Big Data 78

pharmaphorum

AUGUST 11, 2022

There have been great strides made in genomics to refine tools that determine the safest, most effective course of treatments for patients across a number of disease states. Looking at an individual’s genomic profile also provides an understanding of appropriate medication dosage.

Genome 98

Genome Genomics Genetics Drugs 98

The Pharma Data

AUGUST 16, 2021

The antiviral agent incorporates RNA-like building blocks into the RNA genome of the virus. ” Mutations in the genome stop the virus. In the first phase, the viral copying machine, called RNA polymerase, incorporates these building blocks into the RNA genome of the virus.

RNA 52

RNA Drugs Genome Genomics 52

pharmaphorum

JANUARY 24, 2022

That is backed up by a meta analysis of its performance published last year in Nature found that the treatment recommendations delivered by the tool were largely in line with human doctors for several cancer types.

Radiology 109

Radiology Marketing Genome Genomics 109

Drug Discovery World

NOVEMBER 1, 2023

DDW’s Diana Spencer meets Dr Stephen Jones, Research Professor and Group Leader at the EMBL Partnership Institute for Genome Editing Technologies at Vilnius University’s Life Sciences Center. DS: Can you tell us what you do and what you’re working on at the moment?

Gene Editing 59

Gene Editing Research Gene Genome 59

Drug Discovery World

NOVEMBER 27, 2023

Predictable milestones and future perspectives Transposons (genetic elements) have been used to deliver a gene of interest into transcriptionally active sites of the cell line genome leading to rapid cell line development eventually resulting in high titers of the recombinant protein drug.

Production 59

Production Engineer Gene Editing Gene 59

XTalks

MAY 20, 2022

Doctors and physicians rely on the results provided by a clinical scientist to make an accurate prognosis, diagnosis and assessment for a patient’s treatment plan. Interpret medical tests and confer with doctors and physicians for a suitable prognosis and treatment plan. Their work might involve matching blood samples for transfusions.

Scientist 105

Scientist Life Science Clinical Research Doctors 105

pharmaphorum

NOVEMBER 3, 2020

There are no clinical practice guidelines, meaning doctors treat on a case-by-case basis. Another, apparently contradictory, point is that the number of ring 20 diagnoses have actually declined with advances in genome sequencing, which cannot detect the presence of ring chromosomes.

Gene Sequencing 116

Gene Sequencing Gene Genome Genomics 116

The Pharma Data

SEPTEMBER 6, 2021

Genomic data from the phase II CUPISCO study in Cancer of Unknown Primary (CUP), an uncommon type of cancer with high unmet need, could support diagnostics and more personalised treatment plans. In CUP, doctors cannot identify the location of the original (primary) tumour and can only find metastases. Comprehensive genomic profiling.

Genome 52

Genome Genomics HR Hormones 52

Drug Discovery World

JUNE 12, 2023

For instance, if there’s something unique biologically, we surround ourselves with doctors who give us a good insight that this is worth pursuing. With the publications of our other data, our Phase II work, the science has led to a lot of interest from doctors on behalf of their patients.

Research 52

Research In-Vitro Doctors Doctor 52

pharmaphorum

JULY 4, 2022

And this is where modern technologies and data-driven medical informatics can really bridge the gaps in rare disease research,” said Dr Joanne Hackett, head of Genomic and Precision Medicine at IQVIA, during a recent pharmaphorum webinar.

Genome 104

Genome Genomics Research Medicine 104

pharmaphorum

MARCH 19, 2021

Approximately 85% of rare diseases are genetic, offering significant opportunities to develop better treatments as our understanding of the human genome improves 1. However, often rare disease patients are ignored by doctors, researchers, and the general public.

Branding 52

Branding Genome Genomics Genetics 52

The Pharma Data

SEPTEMBER 1, 2021

“Doctors often treat patients who have rheumatoid arthritis with injections or infusions of anti-inflammatory biologic drugs, but those drugs can cause significant side effects when delivered long enough and at high enough doses to have beneficial effects,” said senior investigator Farshid Guilak, PhD, the Mildred B.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

pharmaphorum

JUNE 15, 2021

Every patient, every doctor or nurse, every hospital worker is a human being influenced by their experiences outside of healthcare. centric care model to a more virtual distributed care model that heavily leverages the latest technologies around artificial intelligence, deep learning, data analytics, genomics, home?based

Big Data 52

Big Data Nurses Genome Genomics 52

pharmaphorum

OCTOBER 5, 2021

The time of individuals relying entirely on face-to-face interaction with their doctors is long past. Although junior doctors may be more digitally native, it is possible that there will be more widespread adoption in experienced medical professionals, because they understand the medical and patient end value better.

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Doctors Doctor Marketing Development 131

The Pharma Data

DECEMBER 17, 2020

Dr. Lisa Forbes — his doctor and co-author of a letter describing his case in the Oct. Because he had multiple conditions, his doctors ordered whole genome sequencing to see if they could pinpoint a root cause. WEDNESDAY, Oct. He’s been off insulin since August 2018 — more than two years.

Insulin 52

Insulin Genetics Doctors Doctor 52

The Pharma Data

DECEMBER 29, 2020

” Some patients needed weeks in the hospital before doctors could find a medication that worked. The World Health Organization (WHO) says steps to expand the sequencing of the genome of new variants of the coronavirus are needed as the pandemic enters its second year, the Associated Press reported. ” © 2020 HealthDay.

Genome 52

Genome Genomics Immune Response Doctors 52

Drug Discovery World

AUGUST 16, 2023

The authors therefore recommend against doctors routinely using biopsies taken from primary tumour samples to carry out gene-expression (RNA)-based biomarker tests for guiding the treatment for secondary cancers.

Genetics 52

Genetics Gene Hormones RNA 52

pharmaphorum

NOVEMBER 11, 2020

For pharmaceutical companies, artificial intelligence can help spur drug discovery through finding complex relationships within genomics data. In the US especially, doctors spend much of their time doing administrative tasks that can be automated to save time and reduce errors.

Engineer 139

Engineer Life Science Genome Genomics 139

pharmaphorum

DECEMBER 19, 2022

Theirs is also the issue that therapies can’t be restarted, they have to be continued, and so with no documentation and contacting doctors in Ukraine impossible because either the hospital didn’t exist anymore, or contact was otherwise challenging – Jassem asserted that they could only do their best.

Genome 97

Genome Genomics Development Doctors 97

pharmaphorum

FEBRUARY 26, 2021

Every time a patient with a rare condition walks into a hospital, doctors face the probable challenge of starting from scratch. For instance, the UK government’s 100K Genomes Project has achieved its goal of sequencing the genomes of 100,000 people in 2019.

Drugs 78

Drugs Genome Project Genome Genomics 78

pharmaphorum

OCTOBER 6, 2022

He trained in Molecular Biology and earned a doctorate in Genetics from George Washington University, followed by a postdoctoral fellowship at the National Institute of Aging in the Microarray Core. He served as Director of the Lowe Family Genomics Core at the Johns Hopkins University from 2005-15.

In-Vivo 98

In-Vivo Research Genetics Drugs 98

Pharmaceutical Technology

NOVEMBER 4, 2022

And we're building this Data Commons, bringing in imaging data, genomic data, clinical health record data, which in Scotland is really well annotated already,” says McNeil. All data is anonymised to protect patient confidentiality. We're trying to understand why it’s increasing so much across the world, but Scotland in particular.

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Medicine Development Research Gene 130